Region

Oligonucleotide

Purification Products

Clarity HPLC Information


Purification and Analysis of Synthetic Oligonucleotides

The Clarity BioSolutions LC portfolio includes novel RP-LC and IEX-LC columns for purifying and characterizing synthetic DNA / RNA used in biological research, therapeutic development, and biochemical manufacturing.

 

• Clarity Oligo-SAX: High Capacity Ion-Exchange Analysis and Characterization

 

• Clarity Oligo-XT: High Efficiency LC/MS Analysis Scaling Directly to LC Purification

 

Clarity Oligo-MS™: LC/MS analysis

 

Clarity Oligo-RP™: RP-LC purification and analysis

 

Clarity Oligo-WAX™: IEX-LC purification

 

Oligo-XT


Particle Sizes (µm)1.7, 2.6, 5
Pore Size (Å)100
Compare All Phases

Oligo-XT Phase Information


Clarity Oligo-XT, C18 columns have been designed to provide rugged high performance for the LC/MS characterization of synthetic DNA and RNA samples, alongside purification of these targeted oligos.  With high efficiency levels from the novel core-shell particle design, this new media provides the necessary separation power to accurately resolve closely related oligo sequences. Additionally, this new technology provides excellent sensitivity levels for easier MS quantitation.

  • Novel core-shell particle technology with rugged pH stability from 1-12
  • 2.6 µm particles deliver increased efficiency at reduced backpressures
  • 1.7 µm particles boost performance for UHPLC methodologies
  • 5 µm particles provide extremely low pressure HPLC and Preparative purification solution
  • Seamless scalability between all three particle sizes
PhaseParticle Sizes (µm)Pore Size (Å)Recommended Use
Oligo-MS1.7, 2.6100Rapid LC/MS analysis and QC of synthetic oligonucleotide research reagents and therapeutics
Oligo-RP3, 5, 10110Purification of synthetic oligonucleotide mixtures
Oligo-SAX5N/A
Oligo-WAX10400Preparative purification of synthetic oligonucleotide mixtures
Oligo-XT1.7, 2.6, 5100
Document Type:
Document Type Title
Brochures Axia PrePacked Preparative HPLC and SFC Brochure Add to My Documents
Technical Notes Analysis of Synthetic Oligonucleotides using Quaternary Amine Functionalized, Non-porous Particles - Clarity Oligo-SAX (TN-1206) Add to My Documents
Technical Notes Automated Method Development of Oligonucleotide in Tissues Using Clarity OTX 96-Well Plate and High Resolution Mass Spectrometry (TN-0097) Add to My Documents
Brochures Clarity LC Solutions Add to My Documents
Brochures Improve Your Bioanalytical Assays Today Add to My Documents
Other Ultimate Guide to Reversed Phase HPLC/UHPLC - Column Selectivity Selection Poster Add to My Documents
Technical Notes Avoiding Depurination During Trityl-on Purification (TN-0008) Add to My Documents
Brochures Bulk Media Selection Guide Add to My Documents
Technical Notes Oligonucleotide Therapeutics from Biological Matrices (TN-0048) Add to My Documents
Technical Notes Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column (TN-1200) Add to My Documents
Technical Notes Synthetic Oligonucleotides by LC/MS (TN-1052) Add to My Documents
MSDS Safety Data Sheet for Silica-Based HPLC Columns Add to My Documents
Supporting Docs Allowable Adjustments to Pharmacopoeia Methods Add to My Documents
Supporting Docs Meeting All Your PREP Needs Add to My Documents
Other Protein and Peptide Users Guide Add to My Documents
Supporting Docs HPLC Column Care Guide Add to My Documents
Phase: Particle Size: Pore Size: Length: Internal Diameter:
Loading...

Part Number:00B-4745-AN

Description:Clarity® 5 µm Oligo-XT, LC Column 50 x 2.1 mm, Ea

Required Holder:

Stationary Phase:

Solid Support:

Format:Column

Separation Mode:

Recommended Use:

USP Designation:


 Search Results


Part
Number
Brand Phase Particle
Size (µm)
Pore
Size (Å)
Length (mm) Internal
Diameter (mm)
Price