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One of the World's

Leading HPLC Columns

Luna HPLC Information


One of the World's Leading HPLC Columns

Dependable, ultra-pure silica-based HPLC columns that offer an extensive variety of selectivities which are scalable from micro-bore to preparative and purification scale solutions.

  • Extensive line of rugged USP phases
  • Wide pH stability for long column lifetime and method flexibility
  • Easy method scalability from Fast LC to Preparative and Bulk Purification

New Luna Omega UHPLC

Enhanced with 20 Years of technology, innovation, and experience, Luna Omega 1.6µm columns build upon the Luna legacy to now provide incredible UHPLC performance and selectivity.

With Luna Omega columns you gain:

  • Astounding UHPLC performance and efficiencies
  • Greater separation muscle
  • Better peak shape through an inert foundation
  • Extreme ruggedness and dependability

Luna Omega C18

  • Rugged C18 with focus on strong hydrophobic retention of non-polar and polar compounds.

Luna Omega Polar C18

  • 100 % aqueous stability and enhanced selectivity/retention for polar analytes without diminishing useful non-polar retention

Luna Omega PS C18

  • Unique mixed-mode selectivity with enhanced retention for polar acids, better peak shape for bases and 100% aqueous stability

Luna Omega 5µm

  • High efficiency HPLC particle that allows for direct scalability from UHPLC to HPLC to PREP LC
 

Luna HPLC and PREP

As one of the world’s most recognized HPLC brands, Luna is a high quality, industry standard that is incredibly dependable, batch to batch and column to column. With a highly versatile family of selectivities, Luna stationary phases will help drive your method development and leave you at ease with existing methods.

Phase Description Application
Silica(2) Unbonded silica Non-polar compounds
C5 5 Carbon ligand Good alternative to C8 when less retention is desired
C8(2) C8 ligand optimized for improved peak shape Great starting phase for method development
C18(2) C18 ligand optimized for improved peak shape From capillary LC/MS to process scale Our most popular phase
CN Versatile CN phase For improving the retention of polar compounds
NH2 Rugged and reproducible NH Sugar alcohols, anionic or hydrogen bonding compounds
Phenyl-Hexyl Phenyl phase attached to C6 (hexyl) ligand Unique selectivity for very polar and aromatic compounds
SCX Benzene sulfonic acid Amine and polyamine containing compounds
HILIC Reproducible, cross-linked diol Increased retention and MS sensitivity of polar compounds
PFP(2) Pentafluorophenyl with a C3 (propyl) linkage Highly polar compounds, halogenated compounds and isomers

C18(2)


Particle Sizes (µm)2.5, 3, 5, 10, 15
Pore Size (Å)100
Surface Area (sq. m/g)400
Carbon Load (%)17.5
Compare All Phases

C18(2) Phase Information


Octadecyl silane ligands are bound to the silica surface, making for a very hydrophobic phase with great methylene selectivity. Non-polar endcapping virtually eliminates silanol interactions

PhaseParticle Sizes (µm)Pore Size (Å)Surface Area (sq. m/g)Carbon Load (%)Recommended Use
C183, 5, 1010044019Separation of hydrophobic compounds
C18(2)2.5, 3, 5, 10, 1510040017.5Separation of hydrophobic compounds
C18-E20100N/A
C55, 1010044012.5Separation of extremely hydrophobic compounds
C83, 5, 1010044014.75Separation of very hydrophobic compounds
C8(2)3, 5, 10, 1510040013.5Separation of very hydrophobic compounds
CN3, 5, 101004007Separation of polar compounds
HILIC3, 5200200*5.7Separation of polar compounds
NH23, 5, 101004009.5Separation of polar compounds
Omega C181.6100N/A
Omega Polar C181.6, 5100N/A
Omega PS C181.6, 5100N/A
PFP(2)3, 5100400N/ASeparation of aromatic and halogenated compounds
Phenyl-Hexyl3, 5, 10, 1510040017.5Separation of aromatic compounds
PREP C18(2)10100N/A
PREP C18(3)10100N/A
PREP C410100N/A
PREP C8(2)10100N/A
PREP C8(3)10100N/A
PREP Phenyl-Hexyl10100N/A
PREP Silica(2)10100N/A
PREP Silica(3)10100N/A
SCX5, 101004000.55 % Sulfur LoadSeparation of positively charged compounds
Silica (2)3, 5, 10, 15100400N/ASeparation of polar compounds
Document Type:
Document Type Title
Brochures Axia PrePacked Preparative HPLC and SFC Brochure Add to My Documents
Technical Notes LC/MS/MS Analysis of Underivitized Methylmalonic Acid (MMA) and Succinic Acid in Plasma Using Strata-X-AW and Luna Omega 1.6 μm PS C18 Add to My Documents
Other Clinical Research Solutions Guide Add to My Documents
Brochures Custom Method Development and Optimization Services for Clinical Research Add to My Documents
Technical Notes Optimization Tips for HILIC Analysis of Basic Compounds (TN-1040) Add to My Documents
Technical Notes Determination of Cylindrospermopsin and Anatoxin-a in Drinking Water by UHPLC/MS/MS using a Luna® Omega 1.6 μm Polar C18 (EPA Method 545) Add to My Documents
Technical Notes Determination of Microcystins and Nodularin in Drinking Water by UHPLC/MS/MS using a Luna Omega 1.6 μm Polar C18 (EPA Method 544) Add to My Documents
Brochures Explore Luna HPLC Columns Add to My Documents
Brochures Extend your Analytical and Preparative HPLC/ SFC Column Lifetimes Add to My Documents
Technical Notes Fast and Simple Analysis of Polyphenols in Red Wine (TN-1166) Add to My Documents
Technical Notes Glyphosate Analysis by LC/MS/MS using FMOC Derivitization or Underivitized Method Add to My Documents
Other HPLC/UHPLC Column Phase Selection Chart Add to My Documents
Brochures Improve Your Bioanalytical Assays Today Add to My Documents
Technical Notes Increasing LC-MS MS Sensitivity with Luna HILIC Add to My Documents
Technical Notes LC/MS/MS Analysis of Ethyl Glucuronide (EtG) and Ethyl Sulfate (EtS) from Urine Using a Luna Omega 1.6 μm UHPLC Column (TN-1201) Add to My Documents
Brochures Luna Omega Brochure Add to My Documents
Brochures Pesticide Analysis by GC/LC/Sample Prep Add to My Documents
Other Pharmaceutical Analysis Guide- Formulations Add to My Documents
Technical Notes Rapid Analysis of 125 pesticides from Ground Water by UHPLC-MSMS using Luna Omega 1.6 µm C18 Add to My Documents
Technical Notes Rapid Analysis of 23 Per- and Poly-Fluorinated Alkyl Substances (PFASs) by UHPLC-MS/MS using Luna Omega 1.6 μm PS C18 Add to My Documents
Brochures SecurityGuard Column Protection Family Brochure (UHPLC, HPLC, PREP, SFC) Add to My Documents
Other THE Clinical Application Notebook, Volume 1 Add to My Documents
Technical Notes Vitamin A and E Analysis From Infant Formula Using Luna® 3 μm NH2 per AOAC OMA 2012.10 Add to My Documents
Other A Simple, Rapid Method for teh Analysis of Ethephon from Ketchup using Solid Phase Extraction and LCMSMS Add to My Documents
Technical Notes Achiral Stationary Phase Selectivity under SFC Conditions (TN-1041) Add to My Documents
Brochures Bulk Media Selection Guide Add to My Documents
Technical Notes Change Selectivity, Not the Stationary Phase, for Synthetic Peptide Multi-Step Purifications (TN-1177) Add to My Documents
Technical Notes Glucosinolates from Cruciferous Vegetable Extracts by HPLC/UV (TN-1157) Add to My Documents
Supporting Docs Guidelines for HILIC Method Development Add to My Documents
Technical Notes LC/MS/MS Analysis of Ethyl Glucuronide (EtG) and Ethyl Sulfate (EtS) in Urine using Luna® Omega 5 μm Polar C18 HPLC Column Add to My Documents
Technical Notes LC/MS/MS Analysis of Homocysteine using Luna® Omega 1.6 μm PS C18 UHPLC Column Add to My Documents
Technical Notes LC/MS/MS Analysis of Mitragynine and 7-OH Mitragynine using Luna Omega 1.6 μm PS C18 UHPLC Column Add to My Documents
Supporting Docs Luna 2.5 µm C18(2) HST White Paper Add to My Documents
Supporting Docs Luna and Luna Omega Care and Use Notes Add to My Documents
Technical Notes Metanephrine and Normetanephrine from Plasma by LC/MS/MS (TN-0018) Add to My Documents
Technical Notes Oxytocin (OT) and ARG-Vasopressin (AVP) from Human Plasma by SPE and LC/MS Add to My Documents
Technical Notes Peptide Separations by Cation Exchange HPLC (TN-1024) Add to My Documents
Brochures Preparative Columns Redefined Add to My Documents
MSDS Safety Data Sheet for Silica-Based HPLC Columns Add to My Documents
Technical Notes Screening and Confirmation of Synthetic Cannabinoid Urinary Metabolites using Kinetex Core-Shell Columns and a Luna Fully Porous Column (TN-1179) Add to My Documents
Technical Notes Thiamin Diphosphate (Vitamin B1) from Whole Blood by LC-Fluorescence Add to My Documents
Technical Notes Vitamin B1 and B6 from Whole Blood Add to My Documents
Supporting Docs Allowable Adjustments to Pharmacopoeia Methods Add to My Documents
Brochures AXIA Preparative Family Brochure Add to My Documents
Brochures Luna C18 (3) Add to My Documents
Supporting Docs Luna Column Selection by Ph. Eur. Listings and Tolerances Add to My Documents
Supporting Docs Meeting All Your PREP Needs Add to My Documents
Supporting Docs Meeting All Your SFC Needs Add to My Documents
Technical Notes Metformin HCL by HPLC per the USP Monograph Add to My Documents
Technical Notes Optimization of Preparative Production using Axia™ for Increased Purity, Yield and Productivity (TN-1049) Add to My Documents
Technical Notes Peptide Purification Method Development: Application for the Purification of Bivalirudin (TN-1129) Add to My Documents
Technical Notes Melamine from Food Products by SPE and LC/MS/MS (TN-0019) Add to My Documents
Technical Notes Free Metanephrine (MN) and Normetanephrine (NMN) from Plasma by SPE and LC/MS/MS (TN-0018) Add to My Documents
Brochures Preparative/Process Add to My Documents
Supporting Docs Axia Packed Columns Vs Traditional Packed Preparative Columns (Video) Add to My Documents
Supporting Docs HPLC Column Care Guide Add to My Documents
Phase: Particle Size: Pore Size: Length: Internal Diameter:
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Part Number:00F-4252-C0

Description:Luna® 5 µm C18(2) 100 Å, LC Column 150 x 3.9 mm, Ea

Required Holder:

Stationary Phase:C18 with TMS endcapping

Solid Support:Fully Porous Silica

Format:Column

Separation Mode:Reversed Phase

Recommended Use:Separation of hydrophobic compounds

USP Designation:L1


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