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Oligonucleotide

Purification Products

Clarity HPLC Information


Purification and Analysis of Synthetic Oligonucleotides

The Clarity BioSolutions LC portfolio includes novel RP-LC and IEX-LC columns for purifying and characterizing synthetic DNA / RNA used in biological research, therapeutic development, and biochemical manufacturing.

 

• Clarity Oligo-SAX: High Capacity Ion-Exchange Analysis and Characterization

 

• Clarity Oligo-XT: High Efficiency LC/MS Analysis Scaling Directly to LC Purification

 

Clarity Oligo-MS™: LC/MS analysis

 

Clarity Oligo-RP™: RP-LC purification and analysis

 

Clarity Oligo-WAX™: IEX-LC purification

 

Oligo-WAX


Particle Sizes (µm)10
Pore Size (Å)400
Compare All Phases

Oligo-WAX Phase Information


Clarity Oligo-WAX LC columns were designed with the synthetic DNA/RNA preparative chromatographer in mind.  Oligo-WAX is an advantageous combination of purity, capacity, mechanical strength, cost, and efficiency.

  • Excellent efficiency column results in >90% purities due to good fractionation of closely eluting compounds
  • High loading capacity due to very high density ligand
  • Increase productivity by running at higher flow rates and pressures
  • Columns amenable to HPLC and FPLC systems
PhaseParticle Sizes (µm)Pore Size (Å)Recommended Use
Oligo-MS1.7, 2.6100Rapid LC/MS analysis and QC of synthetic oligonucleotide research reagents and therapeutics
Oligo-RP3, 5, 10110Purification of synthetic oligonucleotide mixtures
Oligo-SAX5N/A
Oligo-WAX10400Preparative purification of synthetic oligonucleotide mixtures
Oligo-XT1.7, 2.6, 5100
Document Type:
Document Type Title
Brochures Axia PrePacked Preparative HPLC and SFC Brochure Add to My Documents
Technical Notes Analysis of Synthetic Oligonucleotides using Quaternary Amine Functionalized, Non-porous Particles - Clarity Oligo-SAX (TN-1206) Add to My Documents
Technical Notes Automated Method Development of Oligonucleotide in Tissues Using Clarity OTX 96-Well Plate and High Resolution Mass Spectrometry (TN-0097) Add to My Documents
Brochures Clarity LC Solutions Add to My Documents
Brochures Improve Your Bioanalytical Assays Today Add to My Documents
Other Ultimate Guide to Reversed Phase HPLC/UHPLC - Column Selectivity Selection Poster Add to My Documents
Technical Notes Avoiding Depurination During Trityl-on Purification (TN-0008) Add to My Documents
Brochures Bulk Media Selection Guide Add to My Documents
Technical Notes Oligonucleotide Therapeutics from Biological Matrices (TN-0048) Add to My Documents
Technical Notes Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column (TN-1200) Add to My Documents
Technical Notes Synthetic Oligonucleotides by LC/MS (TN-1052) Add to My Documents
MSDS Safety Data Sheet for Silica-Based HPLC Columns Add to My Documents
Supporting Docs Allowable Adjustments to Pharmacopoeia Methods Add to My Documents
Supporting Docs Meeting All Your PREP Needs Add to My Documents
Other Protein and Peptide Users Guide Add to My Documents
Supporting Docs HPLC Column Care Guide Add to My Documents
Phase: Particle Size: Pore Size: Length: Internal Diameter:
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Part Number:04K-4451

Description:Clarity® 10 µm Oligo-WAX, Bulk Packing, 1 kg, Ea

Required Holder:

Stationary Phase:

Solid Support:

Format:Unknown / Un-classified

Separation Mode:

Recommended Use:

USP Designation:


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