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Strata-X

Simplified Solid Phase Extraction Solutions

Strata-X Polymeric SPE Information


Capitalize on Cleanliness without Sacrificing Recovery

With Strata™-X polymeric SPE sorbents the guesswork that leads to lengthy method development is eliminated. Unique selectivities have been developed to cover a diverse spectrum of analytes, and simplify the method development process for fast and efficient sample preparation.

  • Tightly retain analytes by several different sorbent-analyte interactions
  • Remove unwanted contaminants including phospholipids for superior chromatography
  • Easily cleanup large volume or viscous samples as well as target analytes that exceed 10 kDa
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X-C, Strong Cation Mixed Mode Phase Detail


Sorbent TypePolymer-based
Surface Area (sq. m/g)800
pKa~0
Target AnalytesWeakly basic compounds
Compare All Phases

X-C, Strong Cation Mixed Mode Phase Information


A strong cation-exchange functionalized polymeric sorbent that allows for complete retention of basic compounds with a pKa less than 10.5, making 100% organic wash conditions possible.  A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.

PhaseSorbent TypeSurface Area (sq. m/g)pKaTarget Analytes
X, Drug B, Strong Cation Mixed Mode Polymer-based800ProprietaryBasic drugs of abuse
X, Drug N, Polymeric Reversed Phase 520N/A
X, Polymeric Reversed Phase Polymer-based800N/ANeutral and aromatics
X, Polymeric Reversed Phase Polymer-based800N/ANeutral and aromatics
X-A, Strong Anion Mixed Mode Polymer-based800~14Weakly acidic compounds
X-AW, Weak Anion Mixed Mode Polymer-based800~9Acidic compounds (i.e.) strong acids
X-C, Strong Cation Mixed Mode Polymer-based800~0Weakly basic compounds
X-C, Strong Cation Mixed Mode Polymer-based800~0Weakly basic compounds
X-CW, Weak Cation Mixed Mode Polymer-based800~4.5Basic compounds, particularly strong bases
X-CW, Weak Cation Mixed Mode Polymer-based800~4.5Basic compounds, particularly strong bases
XL, Polymeric Reversed Phase Polymer-based520N/ANeutrals, aromatics present in viscous samples
XL-A, Strong Anion Mixed Mode Polymer-based520~14Weakly acidic compounds present in viscous samples
XL-AW, Weak Anion Mixed Mode Polymer-based520~9Acidic compounds (i.e. strong acids) present in viscous samples
XL-C, Strong Cation Mixed Mode Polymer-based520~0Weakly basic compounds, present in large volume or viscous samples
XL-CW, Weak Cation Mixed Mode Polymer-based520~4.5Basic compounds (i.e.strong bases) present in viscous samples
Document Type:
Document Type Title
Technical Notes Drugs of Abuse Panel from Urine by GC/MS and LC/MS (TN-0041) Add to My Documents
Other Clinical Research Solutions Guide Add to My Documents
Technical Notes Endothalls in Water by EPA Method 548.1 using SPE and GC/MS (TN-0067) Add to My Documents
Technical Notes Hormones from Drinking Water by LC/MS/MS (TN-1163) Add to My Documents
Technical Notes Improved Recoveries using SPE vs. Liquid-Liquid Extraction (TN-0044) Add to My Documents
Brochures Meet Your SPE Support Team Add to My Documents
Other Pain Panel Applications Guide Add to My Documents
Webinar How to Determine the Best Sample Preparation Technique for your Unique Samples Add to My Documents
Technical Notes A Simplified Approach to Sample Preparation (TN-013) Add to My Documents
Brochures Choose the best Strata-X sorbent for your analysis Add to My Documents
Webinar Solid Phase Extraction Basics Webinar Add to My Documents
Brochures Strata-X Mini Brochure Add to My Documents
Brochures Strata-X vs. Waters Oasis Add to My Documents
Brochures Strata-X-Drug, SPE Sorbents Designed for Drugs of Abuse Analysis Add to My Documents
Brochures Strata-X-Drug B for Drugs of Abuse Add to My Documents
Brochures Quick and Simple Cleanup for Medicinal Chemistry Add to My Documents
Technical Notes Benzodiazepines from Urine and Plasma by LC/MS/MS (TN-0054) Add to My Documents
Other Vitamin Testing Applications Guide Add to My Documents
Technical Notes 41 Pain Management Drugs from Urine by LC/MS/MS (TN-0053) Add to My Documents
Technical Notes A Simple Approach to Automated SPE (TN-014) Add to My Documents
Technical Notes Acidic Drugs from Plasma by HPLC/UV (TN-0036) Add to My Documents
Technical Notes Aggressive Cleanup of Sulfa Drugs (TN-010) Add to My Documents
Other Automated Extraction of Benzodiazepines from Urine and Plasma by LC/MS/MS (Poster) Add to My Documents
Technical Notes Bisphenol A from Water by HPLC/FLD (TN-0040) Add to My Documents
Technical Notes Chiral Separation of Synthetic Cannabinoid Metabolites (TN-1167) Add to My Documents
Technical Notes Chloramphenicol from Shrimp by LC/MS/MS (TN-1081) Add to My Documents
Technical Notes Chloramphenicol from Various Food Matrices by LC/MS/MS (TN-1120) Add to My Documents
Technical Notes Basic Drugs from Biological Matrices (TN-008) Add to My Documents
Technical Notes Evaluation of Newer Technologies for the LC/MS/MS Analysis of Amphetamines (TN-1096) Add to My Documents
Technical Notes Haloacetic Acids from Water by GC/ECD (TN-0039) Add to My Documents
Technical Notes Cleanup of Polar Acids (TN-0037) Add to My Documents
Technical Notes Sulfonamides from Honey by LC/MS/MS (TN-0012) Add to My Documents
Technical Notes Hop Acids from Beer by HPLC/UV (TN-1085) Add to My Documents
Supporting Docs How to Improve Sample Preparation Accuracy, Reproducibility, and Lab-to-Lab Variation with Automation Add to My Documents
Technical Notes Barbiturates from Urine by LC/MS/MS (TN-0045) Add to My Documents
Technical Notes LC/MS/MS Analysis of Immunosuppressants from Whole Blood (TN-1169) Add to My Documents
Technical Notes Metanephrine and Normetanephrine from Plasma by LC/MS/MS (TN-0018) Add to My Documents
Technical Notes Metronidazole from Foaming Facial Cleanser by LC/MS/MS (TN-0049) Add to My Documents
Technical Notes Nicotine, Cotinine, 3-Hydroxycotinine, Nornicotine and Anabasine in Human Urine by LC/MS/MS (TN-1161) Add to My Documents
Technical Notes Oil Dispersants (COREXIT 9527 and 9500) by GC/MS and LC/MS/MS (TN-2046) Add to My Documents
Technical Notes Optimization of Wash/Elution Conditions for Automated SPE of Testosterone from Plasma (TN-0017) Add to My Documents
Technical Notes Pain Management and Illicit Drugs from Oral Fluids by LC/MS/MS (TN-0068) Add to My Documents
Technical Notes Palladium Catalyst Removal from a Suzuki Reaction (TN-0046) Add to My Documents
Technical Notes Digoxin and Digitoxin in Plasma by LC/MS/MS (TN-1099) Add to My Documents
Technical Notes Sudan Dye Contaminants in Spices by HPLC/UV (TN-015) Add to My Documents
Technical Notes Steroids from Urine and Plasma by LC/MS/MS (TN-1096) Add to My Documents
Technical Notes Strata-X General Method for the Extraction of Neutral Compounds (TN-0023) Add to My Documents
Technical Notes Strata-X-A General Method for the Extraction of Weak Acids (TN-0035) Add to My Documents
Technical Notes Strata-X-AW General Method for the Extracion of Weak Acids (TN-0025) Add to My Documents
Technical Notes Strata-X-AW General Method for the Extraction of Any Acid (TN-0024) Add to My Documents
Technical Notes Strata-X-AW General Method for the Extraction of Weak Acids Add to My Documents
Technical Notes Strata-X-C General Method for the Extraction of Weak Bases (TN-0026) Add to My Documents
Technical Notes Strata-X-CW General Method for the Extraction of Any Base (TN-0027) Add to My Documents
Technical Notes Strata-X-CW General Method for the Extraction of Weak Bases (TN-0028) Add to My Documents
Technical Notes Strata-XL General Method for the Extraction of Neutral Compounds (TN-0029) Add to My Documents
Technical Notes Strata-XL-A General Method for the Extraction of Weak Acids (TN-0038) Add to My Documents
Technical Notes Strata-XL-AW General Method for the Extraction of Any Acid (TN-0030) Add to My Documents
Technical Notes Strata-XL-AW General Method for the Extraction of Weak Acids (TN-0031) Add to My Documents
Technical Notes Strata-XL-C General Method for the Extraction of Weak Bases (TN-0032) Add to My Documents
Technical Notes Strata-XL-CW General Method for the Extraction of Any Base (TN-0033) Add to My Documents
Technical Notes Strata-XL-CW General Method for the Extraction of Weak Bases (TN-0034) Add to My Documents
Technical Notes Synthetic Cannabinoids and Their Metabolites from Urine by LC/MS (TN-1154) Add to My Documents
Technical Notes Testosterone from Human Serum by LC/MS/MS (TN-1103) Add to My Documents
Technical Notes Tricyclic Antidepressants from Plasma by LC/MS/MS (TN-0056) Add to My Documents
Technical Notes Testosterone (Total) from Human Serum by UHPLC/MS/MS (TN-1103) Add to My Documents
Technical Notes Bianalytical Sample Pre-treatment (TN-0064) Add to My Documents
Supporting Docs Declaration of Conformity Add to My Documents
Phase: Sorbent Mass:
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Part Number:8B-S029-TBJ

Description:Strata™-X-C 33 µm Polymeric Strong Cation, 30 mg / 3 mL, Tubes , 50/Pk

Sorbent Type:Polymer-based

Format:Tube

Phase:Polymeric strong cation exchange

Target Analytes:Weakly basic compounds

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