Region

Oligonucleotide

Purification Products

Clarity (SPE) Filtration Information


Isolation and Purification of Synthetic Oligonucleotides

The Clarity BioSolutions sample preparation portfolio is composed of unique solid phase extraction chemistries packed in 96-well plate and cartridge formats for use with specially formulated buffers for the extraction of DNA and RNA from synthetic cocktails as well as biological matrices.


 

  • Clarity OTX™: Isolation of therapeutics for bioanalysis

  • Clarity QSP™: Rapid trityl-on purification

  • Clarity RP-Desalting™: Quick salt and reagent removal
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Membrane Detail


Membrane Information


High-Throughput Purification

Purify trityl-on synthetic DNA or RNA samples in 20 minutes using Clarity QSP™ 96-well plate and buffer system. Final elution delivers >90 % typical purities/recoveries for in vivo applications and downstream analysis by LC/MS or CE.

  • Amenable to parallel processing
  • For oligos 10-100mer
  • Formats for 200 nmole – 25 µmole synthesis loads

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Document Type:
Document Type Title
Technical Notes Automated Method Development of Oligonucleotide in Tissues Using Clarity OTX 96-Well Plate and High Resolution Mass Spectrometry (TN-0097) Add to My Documents
Brochures Clarity QSP Add to My Documents
MSDS AL0-8280_Clarity QSP DNA Buffer SDS Add to My Documents
MSDS AL0-8282_Clarity QSP RNA Buffer SDS Add to My Documents
MSDS AL0-8579_Clarity OTX Lysis Loading Buffer SDS Add to My Documents
Technical Notes Avoiding Depurination During Trityl-on Purification (TN-0008) Add to My Documents
Brochures Clarity OTX Add to My Documents
Supporting Docs Clarity OTX User’s Guide Add to My Documents
Supporting Docs Clarity QSP User’s Guide (DNA) Add to My Documents
Supporting Docs Clarity QSP User’s Guide (RNA) Add to My Documents
Technical Notes Trityl-on RNA and DNA Purification (TN-0009) Add to My Documents
MSDS KS0-8494_Clarity OTX Elution Buffer SDS (for kit) Add to My Documents
MSDS KS0-8494_Clarity OTX Equilibration Buffer SDS (for kit) Add to My Documents
MSDS KS0-8494_Clarity OTX Wash Buffer SDS Add to My Documents
MSDS KS0-8494_Clarity OTX Wash Buffer SDS (for kit) Add to My Documents
Technical Notes Oligonucleotide Therapeutics from Biological Matrices (TN-0048) Add to My Documents
Supporting Docs Collection Plate and Sealing Mat Selection Guide Add to My Documents
Other Protein and Peptide Users Guide Add to My Documents
Technical Notes RNA Sample Preparation and High Throughput Purification for TBDMS and TOM Chemistries (TN-0016) Add to My Documents
Supporting Docs SPE 10, 12, and 24 Position Vacuum Manifold Instructions Add to My Documents
Supporting Docs SPE 96-Well Vacuum Manifold Add to My Documents
Filter Type: Filter Membrane: Internal Diameter (mm): Pore Size (µm):
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Part Number:8E-S102-DGS

Description:Clarity® 30 µm QSP, 50 mg / well, 96-Well Plates , 40/Pk


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