• Extends Sub-2µm & Core-shell Column
  • For pressures up to 20,000 PSI
  • Easy to use

Protect Your Investment

With SecurityGuard ULTRA, contaminants and micro particulates are trapped in guard cartridge, instead of your expensive column. The extremely low dead volume (<0.3 µL) of this unique guard design minimizes sample peak dispersion to maintain column performance without altering your chromatography results.

When contaminates and particulates build up at the head of your column, system pressures dramatically increase. By simply replacing the SecurityGuard ULTRA cartridge instead of your column you are able to regain normal operating conditions and reclaim original column performance.

Watch our SecurityGuard ULTRA Videos

SecurityGuard ULTRA Installation and Replacement Videos

Technical Documents:

Document Type:
Document Type Title
Brochures Custom Method Development and Optimization Services for Clinical Research


Meet PhenoLogix, our full-service analytical support lab that is ready to help with method development and optimization for the most challenging clinical research applications.

Brochures SecurityGuard Column Protection Family Brochure (UHPLC, HPLC, PREP, SFC)


Get complete protection for your UHPLC, HPLC, SFC and Preparative columns with Securityguard universal guard cartridge system

Technical Notes Antidepressants and Metabolites from Urine by UHPLC-MS/MS


This work, performed by American Clinical Solutions, describes an effective and sensitive LC/MS/MS method for the quantification of several antidepressants from urine including amitriptyline, bupropion, citalopram, clomipramine, doxepin, duloxetine, fluoxetine, imipramine, paroxetine, and venlafaxine.

Other Safety Data Sheet for Silica-Based HPLC Columns


Safety Data Sheet for Silica-Based HPLC Columns

Brochures SecurityGuard ULTRA Brochure


SecurityGuard ULTRA Brochure

Supporting Docs Allowable Adjustments to Pharmacopoeia Methods


Allowable adjustments to pharmacopoeia (USP and Ph. Eur.) isocratic and gradient methods

Technical Notes SecurityGuard ULTRA Dramatically Extends UHPLC Column Lifetimes (TN-1125)


An ultra-high performance column protection system, specifically designed for UHPLC systems using sub-2 μm and core-shell particle columns, can be used to extend column lifetime (saving both money and time through less frequent column replacement), while minimizing system troubleshooting and downtime.

Supporting Docs SecurityGuard ULTRA Installation Instructions


SecurityGuard ULTRA Installation Instructions

Supporting Docs SecurityGuard Ultra Reference Sheet


SecurityGuard Ultra Reference Sheet

Supporting Docs HPLC Column Care Guide


HPLC Column Care Guide

Part Number:AJ0-9000

Description:SecurityGuard ULTRA Holder, for UHPLC Columns 2.1 to 4.6mm ID, Ea

Technique:High Performance Liquid Chromatography (HPLC)

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