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U.S. Patent No. 7, 119, 145

 

 

Capitalize on Cleanliness without Sacrificing Recovery

 

With Strata™-X polymeric SPE sorbents the guesswork that leads to lengthy method development is eliminated. Unique selectivities have been developed to cover a diverse spectrum of analytes, and simplify the method development process for fast and efficient sample preparation.

  • Tightly retain analytes by several different sorbent-analyte interactions
  • Remove unwanted contaminants including phospholipids for superior chromatography
  • Large particle, large pore options available for large volume or viscous samples as well as target analytes that exceed 10 kDa

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X-A, Strong Anion Mixed Mode phase information

X-A, Strong Anion Mixed Mode phase detail

A strong anion-exchange functionalized polymeric sorbent that allows for complete retention of acidic compounds with a pKa >3, making 100% organic wash conditions possible.

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Technical Specifications:

Phase Sorbent Type Surface Area (sq. m/g) pKa Target Analytes
X, Drug B, Strong Cation Mixed Mode Polymer-based 800 Proprietary Basic drugs of abuse
X, Drug N, Polymeric Reversed Phase 520 N/A
X, Polymeric Reversed Phase Polymer-based 800 N/A Neutral and aromatics
X, Polymeric Reversed Phase Polymer-based 800 N/A Neutral and aromatics
X-A, Strong Anion Mixed Mode Polymer-based 800 ~14 Weakly acidic compounds
X-AW, Weak Anion Mixed Mode Polymer-based 800 ~9 Acidic compounds (i.e.) strong acids
X-C, Strong Cation Mixed Mode Polymer-based 800 ~0 Weakly basic compounds
X-C, Strong Cation Mixed Mode Polymer-based 800 ~0 Weakly basic compounds
X-CW, Weak Cation Mixed Mode Polymer-based 800 ~4.5 Basic compounds, particularly strong bases
X-CW, Weak Cation Mixed Mode Polymer-based 800 ~4.5 Basic compounds, particularly strong bases
XL, Polymeric Reversed Phase Polymer-based 520 N/A Neutrals, aromatics present in viscous samples
XL-A, Strong Anion Mixed Mode Polymer-based 520 ~14 Weakly acidic compounds present in viscous samples
XL-AW, Weak Anion Mixed Mode Polymer-based 520 ~9 Acidic compounds (i.e. strong acids) present in viscous samples
XL-C, Strong Cation Mixed Mode Polymer-based 520 ~0 Weakly basic compounds, present in large volume or viscous samples
XL-CW, Weak Cation Mixed Mode Polymer-based 520 ~4.5 Basic compounds (i.e.strong bases) present in viscous samples

Technical Documents:

Document Type:
document type title
Brochures Simplified SPE Solutions Brochure

Summary

Simplified SPE Solutions Brochure

Supporting Docs Free Sample of Strata-X-Drug

Summary

Free Sample of Strata-X-Drug B or Strata-X-Drug N for drugs of abuse

Technical Notes

Summary

Improved Clean Up and Recovery of Pharmaceutical Compounds From Plasma using Strata-X Solid Phase Extraction (SPE) vs. Traditional Liquid-Liquid Extraction Methods

Technical Notes A Simplified and Streamlined Approach to Solid Phase Extraction using Strata™-X-Drug B for SAMHSA’s Low Cutoff Drugs of Abuse Panel

Summary

A Simplified and Streamlined Approach to Solid Phase Extraction using Strata™-X-Drug B for SAMHSA’s Low Cutoff Drugs of Abuse Panel

Technical Notes Automated, High-Throughput Analysis of Benzodiazepines from Urine and Plasma using Strata™-X 96-Well Plate Solid Phase Extraction (SPE) and Kinetex® Core-Shell Technology HPLC/UHPLC Columns

Summary

Automated, High-Throughput Analysis of Benzodiazepines from Urine and Plasma using Strata™-X 96-Well Plate Solid Phase Extraction (SPE) and Kinetex® Core-Shell Technology HPLC/UHPLC Columns

Technical Notes Improved Clean up and Recovery of Pharamaceutical Compounds from Plasma using Strata-X Solid Phase Extraction (SPE) versus Traditional Liquid-Liquid Extraction Methods

Summary

Improved Clean up and Recovery of Pharamaceutical Compounds from Plasma using Strata-X Solid Phase Extraction (SPE) versus Traditional Liquid-Liquid Extraction Methods

Brochures Clinical Research Applications Guide

Summary

Clinical Research Applications Guide

Brochures Strata-X-Drug B for Drugs of Abuse

Summary

Strata-X-Drug B for Drugs of Abuse

Brochures Strata-XL for Medicinal Chemistry

Summary

Strata-XL - large pore and particle sorbent for medicinal chemistry applications

Supporting Docs Sample Preparation Webinar from Phenomenex and C&E News

Summary

Sample Preparation Webinar from Phenomenex and C&E News

Supporting Docs Solid Phase Extraction Basics Webinar

Summary

Solid Phase Extraction Basics Webinar from Gilson and Phenomenex

Technical Notes Aggressive Cleanup of Sulfa Drugs

Summary

This technical note demonstrates the effective extraction of sulfa drugs from plasma using the polymeric SPE sorbent strata-X-C

Technical Notes Bisphenol A from Water

Summary

Extraction of Bisphenol A from water using the polymeric SPE sorbent Strata™-X

Technical Notes Efficient Extraction of Basic Drugs from Biological Matrices

Summary

Efficient extraction of basic drugs from biological sample matrices such as urine and plasma using a polymeric cationic mixed-mode sorbent strata-X-C

Technical Notes Extraction of Haloacetic acids

Summary

The extraction and analysis of haloacetic acids, specifically those specified in EPA Method 552.1, are effectively extracted and concentrated from water samples by a new high capacity polymeric strong anion exchange SPE sorbent

Technical Notes Highly Reproducible Extraction and Analysis of Sulfonamides from Honey using Strata-X-C

Summary

Highly Reproducible Extraction and Analysis of Sulfonamides from Honey using Strata™-X*-C Polymeric SPE Sorbent and Gemini® C18 HPLC Column

Technical Notes Metanephrine and normetanephrine are extracted from plasma using Strata-X-CW

Summary

Metanephrine and normetanephrine are extracted from plasma using Strata-X-CW

Technical Notes Rapid and Reproducible Extraction of Acrylamide in French Fries using a Single SPE Sorbent - strata™-X-C

Summary

Rapid and Reproducible Extraction of Acrylamide in French Fries using a Single SPE Sorbent - strata™-X-C

Technical Notes Simplified Approach to Sample Preparation

Summary

Outlines a simple approach for successful solid phase extraction method development

Technical Notes Solid Phase Extraction for Detection of Sudan Dye Contaminants in Spices with HPLC/UV Detection

Summary

Solid Phase Extraction for Detection of Sudan Dye Contaminants in Spices with HPLC/UV Detection

Technical Notes Strata-X-Drug B for SAMHSA's Low Cutoff Drugs of Abuse Panel

Summary

Strata-X-Drug B for SAMHSA's Low Cutoff Drugs of Abuse Panel

Brochures Strata-X Versus Oasis

Summary

See how Strata-X compares against Oasis HLB

Brochures Strata-X-Drug

Summary

Strata-X-Drug polymeric sorbents for drugs of abuse

Supporting Docs Small Molecule SPE Method Development Chart

Summary

Small Molecule SPE Method Development Chart

Technical Notes Evaluation of Newer Technologies for the LC/MS/MS Analysis of Amphetamines using Strata™-X-Drug B Solid Phase Extraction (SPE) and Kinetex® Core-Shell HPLC /UHPLC Columns

Summary

Evaluation of Newer Technologies for the LC/MS/MS Analysis of Amphetamines using Strata™-X-Drug B Solid Phase Extraction (SPE) and Kinetex® Core-Shell HPLC /UHPLC Columns

Technical Notes Extraction of Polar Acids

Summary

This technical note describes a new polymeric strong anion exchange sorbent that dramatically improves the recoveries and cleanup of weak acids as compared to a weak anion exchange SPE sorbent

Technical Notes Improved Extraction and LC/MS/MS Analysis of Barbiturates from Urine Samples using Strata™-X-Drug N SPE and Kinetex® Core-Shell HPLC/UHPLC Columns

Summary

Improved Extraction and LC/MS/MS Analysis of Barbiturates from Urine Samples using Strata™-X-Drug N SPE and Kinetex® Core-Shell HPLC/UHPLC Columns

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