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Proton Pump Inhibitors Including Rabeprazole and Pantoprazole by Chiral HPLC (TN-1102)


Abstract:
This technical note demonstrates the successful separation of protein pump inhibitors (PPI) Omeprazole, Lansoprazole, Rabeprazole, and Pantoprazole using Lux polysaccharide-based columns. These chiral separations indicate the potential to prepare enantiomerically pure forms of racemic active ingredients Pantoprazole (Protonix) and Rabeprazole (AcipHex) using chiral chromatography.
Document Type:
Technical Notes
Industries:
Pharmaceutical/Biopharmaceutical
Techniques:
HPLC / UHPLC
Brands:
Lux
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