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Post-Translational Modifications of Intact IgG by HPLC/UHPLC and GFC/SEC (TN-1118)


Abstract:
For the analysis of large, intact proteins like recombinant IgG therapeutics, Phenomenex offers two bioseparation product lines (Aeris and BioSep) for improved solutions in identifying low-level post-translational modifications. Aeris WIDEPORE is a reversed phase core-shell HPLC/UHPLC column that features improved resolution and recovery versus traditional fully porous 300 Å media. BioSep columns offer high performance gel filtration separations that offer improved resolution and inertness versus other aqueous GFC columns.
Document Type:
Technical Notes
Industries:
Pharmaceutical/Biopharmaceutical
Techniques:
HPLC / UHPLC
Brands:
BioSep-SEC-S Aeris
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