1Terfenadine |
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2Terfenadine |
Compound Name Terfenadine |
CID 5405 |
Molecular Formula C32H41NO2 |
Molecular Weight 471 |
No. Chiral Centers: 1 |
No. Hydrogen Bond Acceptors 3 |
No. Hydrogen Bond Donors 2 |
1Terfenadine |
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2Terfenadine |
Compound Name Terfenadine |
CID 5405 |
Molecular Formula C32H41NO2 |
Molecular Weight 471 |
No. Chiral Centers: 1 |
No. Hydrogen Bond Acceptors 3 |
No. Hydrogen Bond Donors 2 |
Column: | ||||||||
Brand Name: | ||||||||
Part No: | ||||||||
Phase Name: Cellulose-1 | ||||||||
Elution Type: Isocratic | ||||||||
Mobile Phase: A: Methanol with 0.1% DEA B: CO2 | ||||||||
Gradient Profile:
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Flow Rate: 50 mL/min | ||||||||
Temperature: 35°C | ||||||||
Detection: UV-Vis Abs.-Diode Array (PDA) @ 220 nm (22°C) | ||||||||
Sample Note: Application using combination of UV-Vis detector red trace) and PDR-Chiral Advanced Laser Polarimeter blue trace) showing 3 purification cycles. Courtesy of PDR-Chiral, Inc.
105mg in 3.5mL on-column injection of Terfenadine. |