HPLC/GC Approved Syringe Filters
Quality filtration products from Phenomenex offer a convenient and inexpensive way to clarify all your samples for peace of mind and improved analytical results. Phenex™ syringe filters are designed for efficient and cost-effective rapid filtration of almost any solution prior to analysis, and are optimized for superior flow rates and high-thoughput.
The Phenex Advantage
- Maximum chemical compatibility
- Excellent flow rate
- Certified quality
- Particulate-free
- Low protein absorption
- Minimum extractables
- High total throughput
- 100 % integrity tested
- Low hold-up volume
- Bi-directional use

Phenex Membranes
| Membrane Type |
Recommended Applications |
| RC (Regenerated Cellulose) |
Hydrophilic Regenerated Cellulose filter membranes are compatible with a very broad range of aqueous and mixed-organic solutions, making them one of the most universal filter materials used prior to chromatography. Phenex-RC filters also exhibit fast-flow and ultra-low protein and non-specific binding characteristics. |
| PTFE, Teflon ® (Polytetrafluoroethylene) |
Phenex-PTFE membranes are inherently hydrophobic and excellent for filtration of 100 % organic or highly acidic or basic samples. |
PES (Polyethersulfone) |
Polyethersulfone membranes exhibit very fast-flow and ultra-low protein binding characteristics and are ideally suited for use in many life science clarification applications such as filtering critical biological samples, tissue culture media, additives and buffers. |
| NY (Nylon) |
Nylon has inherent hydrophilic characteristics and works well for filtration of many aqueous and mixed-organic sample types. For applications that require low protein or non-specific binding characteristics, Phenomenex recommends Phenex-RC Regenerated Cellulose filters. |
CA (Cellulose Acetate) |
Cellulose Acetate membranes exhibit ultra-low protein binding and are broadly used in the filtration of biological samples. In combination with a glass pre-filter (Phenex-GF/CA), this membrane is excellent for filtration of tissue culture media, general biological sample filtration and clarification. |
GF (Glass Fiber) |
Phenex-GF Glass Fiber filters are made of inert borosilicate glass and have a nominal 1.2 μm pore size. They are commonly used with highly viscous samples or samples that contain high concentrations of particulate matter (e.g. food analysis, biological samples, soil samples, fermentation broth samples, removal of yeasts, molds, etc.). Can be used alone or in series with other Phenex filter membranes such as the 0.45 μm pore Phenex-RC filter to reduce clogging of the membrane and optimize flow. |
Simple Selection
| Application / Sample |
Recommended Filter |
First Alternative |
Second Alternative |
| HPLC and GC Sample Prep |
RC |
PTFE |
PES |
| Aggressive or Pure Organic Solvents |
PTFE |
RC |
NY |
| Protein Analysis/ Biological Samples |
PES |
RC |
GF/CA |
| High Particulate Loads |
RC |
NY |
PTFE |
| Environmental Methods |
RC |
PTFE |
NY |
| Food and Beverage |
RC |
PTFE |
NY |
| Clinical / Toxicology |
RC |
PES |
NY |
| Dissolution Testing |
RC |
PTFE |
NY |
| Ion Chromatography |
RC |
PES |
PTFE |
| Trace Metals (ICP-MS, AAS) |
RC |
PES |
NY |
| Capillary Electrophoresis (CE) |
RC |
PES |
NY |
| Tissue Cultures, Media, Buffers |
GF/CA |
PES |
RC |
| For high load and particulate-laden samples you may consider placing a Glass Fiber (GF) pre-filter in line with the membrane syringe filter of your choice. |