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What is the advantage of running bioZen columns at elevated temperatures?

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BIOZEN HPLC UHPLC REVERSED PHASE PHARMA

Last Updated: 4/20/2018

Proteins tend to diffuse very slowly due to their large size, which can make peaks
appear broad, even on well optimized columns. By increasing the temperature, the
diffusion coefficient of the solvents in the mobile phase are reduced, allowing for
faster mass transfer of the protein analytes, resulting in better peak shapes. A further
advantage of using high temperature is that selectivity can be manipulated by altering
temperature, allowing for better separations in some cases