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Applications
Gradient Separation of a Cold Mix on Gemini C18
16770
Separation Mode: Reversed Phase
Reversed Phase
C18
HPLC
Analgesics, Opioid
Pharmaceutical
Therapeutic / Clinical

Applications

Gradient Separation of a Cold Mix on Gemini C18
Analytes
1Phenylephrine
2Maleic acid
3Acetaminophen
4Chlorpheniramine
5Dextromethorphan
Compound Name
Neosympatol
CID
5284443
Molecular Formula
C9H14ClNO2
Molecular Weight
203
No. Hydrogen Bond Acceptors
3
No. Hydrogen Bond Donors
4
Details
LC Conditions (App ID: 16770)
Column:
Brand Name:
Part No:
Phase Name:
C18
Elution Type:
Gradient
Mobile Phase:
A: 10 mM Phosphate Buffer, pH 2.5
B: Acetonitrile
Gradient Profile:
Step No.Time(min)%A%B
10955
2154060
3174060
417.01955
520955
Flow Rate:
1 mL/min
Temperature:
22°C
System:
Agilent (HP) HPLC
Detection:
UV-Vis Abs.-Diode Array (PDA) @ 215 nm (22°C)
Sample Note:
Gradient separation of four analytes in cold remedy on Gemini C18: Phenylephrine, Acetaminophen, Chlorpheniramine and Dextromethorphan and impurity of Maleic acid

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