| 1Ibuprofen |
|---|
| 2Valerophenone |
| 3Ibuprofen related compound C |
Compound Name Ibuprofen |
CID 3672 |
Molecular Formula C13H18O2 |
Molecular Weight 206 |
No. Chiral Centers: 1 |
No. Hydrogen Bond Acceptors 2 |
No. Hydrogen Bond Donors 1 |
Applications
Ibuprofen by HPLC on Luna 5um C18(2) 250x4.6mm
19612
Separation Mode: Reversed Phase
Reversed Phase
C18(2)
HPLC
Anti-Inflammatory Agents, Non-Steroidal
Clinical
Pharmaceutical/Biopharmaceutical
Pharmaceutical
Therapeutic / Clinical
Analytes
Details
LC Conditions (App ID: 19612)
Column: | ||||||
Brand Name: | ||||||
Part No: | ||||||
Phase Name: C18(2) | ||||||
Elution Type: Isocratic | ||||||
Mobile Phase: A: 600:400 ACN:Water with 4g chloroacetic acid adjusted to pH 3.0 with ammonium hydroxide | ||||||
Gradient Profile:
| ||||||
Flow Rate: 2 mL/min | ||||||
Temperature: 30°C | ||||||
Detection: UV-Vis Abs.-Variable Wave.(UV) @ 254 nm (22°C) | ||||||
Sample Note: The USP Resolution requirement between any two peaks is not less than 2.5, and the tailing factor for any individual peak is not more than 2.5. On the LUNA 5um C18(2) the resolution between Ibuprofen and Valerophenone is 7.55; valerophenone and Ibuprofen related compound C is 6.11. The tailing factors for Ibuprofen, Valerophenone and Ibuprofen related compound C are 1.2, 1.45, and 1.26, respectively. The max back pressure was 215 bar. |
Order Items Used in This Application
00G-4252-E0
Luna 5 µm C18(2) 100 Å, LC Column 250 x 4.6 mm, Ea
Qty:
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