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Applications
Methadone on Lux 5µm Cellulose-2 by SFC
21200
Separation Mode: Chiral
Chiral
Cellulose-2
HPLC
Analgesics, Opioid
Pharmaceutical/Biopharmaceutical
Chemical Compound
Therapeutic / Clinical
Therapeutic / Clinical

Applications

Methadone on Lux 5µm Cellulose-2 by SFC
Analytes
1Methadone
2Methadone
Compound Name
Methadone
CID
4095
Molecular Formula
C21H27NO
Molecular Weight
309
No. Chiral Centers:
1
No. Hydrogen Bond Acceptors
2
Details
LC Conditions (App ID: 21200)
Column:
Brand Name:
Part No:
Phase Name:
Cellulose-2
Elution Type:
Isocratic
Mobile Phase:
A: CO2/(Isopropanol + 0.5% IPA) 80:20 (v/v)
Gradient Profile:
Step No.Time(min)%A
10100
Flow Rate:
3 mL/min
Temperature:
30°C
Detection:
UV-Vis Abs.-Diode Array (PDA) @ 220 nm (30°C)
Sample Note:
Courtesy of Katrijn De Klerck, Debby Mangelings and Yvan Vander Heyden, Department of Analytical Chemistry and Pharmaceutical Technology, Vrije Universiteit Brussel, Brussels, Belgium. Results of this analysis yielded: Alpha >1.1 and Resolution >1.5 SecurityGuard™ Guard Cartridge System extends column lifetime. - SecurityGuard Cartridges, Lux Cellulose-2, 4 x 3.0mm ID, 10/Pk Part No.: AJ0-8366 - Holder Part No.: KJ0-4282

Order Items Used in This Application

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