Chloroquine
LC Conditions
Column
Chirex (S)-VAL and (R)-NEA, LC Column 250 x 4.6 mm, Ea
Brand
Chirex
Part No
00G-3014-E0
Phase Name
3014 (S)-valine and (R)-1-(alpha-naphthyl)ethylamine
Elution Type
Isocratic
Mobile Phase
A: Hexane/Dichloroethane/Ethanol-TFA (50:35:15) w/ ethanol-TFA (20:1)
Gradient Profile
Step No.
Time(min)
%A
%B
1
0
100
0
Flow Rate
1.00 mL/min
Temperature
22°C
Detection
UV-Vis Abs.-Variable Wave.(UV) @ (22°C)
Detection Info
Order Items Used in This Application
- 1. Chloroquine
- 2. Chloroquine
-OEChem-06211003152D<br><br> 48 49 0 1 0 0 0 0 0999 V2000<br> 9.8602 4.0068 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -2.5173 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 0.9827 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 3.9827 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 -0.5173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 -1.0173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 0.4827 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0<br> 4.5981 -2.0173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 0.9827 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -3.5173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -2.0173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 1.9827 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1962 2.4827 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -4.0173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -2.5173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 2.4827 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1962 3.4827 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0901 1.9480 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 3.4827 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0901 4.0173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.9962 2.4618 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.9962 3.5035 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.6762 -1.0999 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.0747 -0.4097 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.3860 -0.4347 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.9875 -1.1250 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 1.1027 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.8101 -2.5999 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.2087 -1.9097 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.8671 0.6727 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.9081 1.5196 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.0611 1.2927 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2881 0.4457 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.9441 -4.0999 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.3426 -3.4097 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.2646 -1.5424 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.4675 -1.5424 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.5560 -3.4804 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3291 -4.3273 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.1760 -4.5543 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.6900 -1.9804 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.4631 -2.8273 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3100 -3.0543 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.9272 2.1727 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0829 1.3280 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.9272 3.7927 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0829 4.6373 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.5319 2.1498 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1 22 1 0 0 0 0<br> 2 8 1 0 0 0 0<br> 2 10 1 0 0 0 0<br> 2 11 1 0 0 0 0<br> 3 7 1 0 0 0 0<br> 3 12 1 0 0 0 0<br> 3 30 1 0 0 0 0<br> 4 17 2 0 0 0 0<br> 4 19 1 0 0 0 0<br> 5 6 1 0 0 0 0<br> 5 7 1 0 0 0 0<br> 5 23 1 0 0 0 0<br> 5 24 1 0 0 0 0<br> 6 8 1 0 0 0 0<br> 6 25 1 0 0 0 0<br> 6 26 1 0 0 0 0<br> 7 9 1 0 0 0 0<br> 7 27 1 0 0 0 0<br> 8 28 1 0 0 0 0<br> 8 29 1 0 0 0 0<br> 9 31 1 0 0 0 0<br> 9 32 1 0 0 0 0<br> 9 33 1 0 0 0 0<br> 10 14 1 0 0 0 0<br> 10 34 1 0 0 0 0<br> 10 35 1 0 0 0 0<br> 11 15 1 0 0 0 0<br> 11 36 1 0 0 0 0<br> 11 37 1 0 0 0 0<br> 12 13 2 0 0 0 0<br> 12 16 1 0 0 0 0<br> 13 17 1 0 0 0 0<br> 13 18 1 0 0 0 0<br> 14 38 1 0 0 0 0<br> 14 39 1 0 0 0 0<br> 14 40 1 0 0 0 0<br> 15 41 1 0 0 0 0<br> 15 42 1 0 0 0 0<br> 15 43 1 0 0 0 0<br> 16 19 2 0 0 0 0<br> 16 44 1 0 0 0 0<br> 17 20 1 0 0 0 0<br> 18 21 2 0 0 0 0<br> 18 45 1 0 0 0 0<br> 19 46 1 0 0 0 0<br> 20 22 2 0 0 0 0<br> 20 47 1 0 0 0 0<br> 21 22 1 0 0 0 0<br> 21 48 1 0 0 0 0<br>M END
Compound Name
Chloroquine
CID
2719
Molecular Formula
C18H26ClN3
Molecular Weight
319
No. Hydrogen Bond Acceptors
3
No. Hydrogen Bond Donors
1
Similar Applications
Reversed Phase
Rapid Sample Extraction of Chloroquine, Hydroxychloroquine, and Desethylchloroquine from Serum for LC-MS/MS Analysis
Kinetex 2.6 µm F5 100 Å, LC Column 50 x 2.1 mm, Ea
25942
Reversed Phase
USP Chloroquine Phosphate Assay on Kinetex 5 µm C18 150 x 4.6 mm - System Suitability
Kinetex 5 µm C18 100 Å, LC Column 150 x 4.6 mm, Ea
25925
Reversed Phase
USP Chloroquine Phosphate Assay on Kinetex 5 µm C18 150 x 4.6 mm - Standard Solution
Kinetex 5 µm C18 100 Å, LC Column 150 x 4.6 mm, Ea
25924
Reversed Phase
USP Chloroquine Phosphate Assay on Luna 5 µm C18(2) 150 x 4.6 mm - System suitability
Luna 5 µm C18(2) 100 Å, LC Column 150 x 4.6 mm, Ea
25923
Reversed Phase
USP Chloroquine Phosphate Assay on Luna 5 µm C18(2) 150 x 4.6 mm - Standard Solution
Luna 5 µm C18(2) 100 Å, LC Column 150 x 4.6 mm, Ea
25922
Reversed Phase
Analysis of Chloroquine and Its Metabolite by LC-MS/MS using Kinetex® Core-Shell F5 LC Columns
Kinetex 2.6 µm F5 100 Å, LC Column 50 x 2.1 mm, Ea
25873
Reversed Phase
Chloroquine Phosphate Tablet - USP Assay on Luna 5 µm C18(2) 150 x 4.6 mm
Luna 5 µm C18(2) 100 Å, LC Column 150 x 4.6 mm, Ea
25863