Guaifenesin Tablets - Modified USP Method

LC Conditions

Column

Gemini 5 µm C18 110 Å, LC Column 150 x 4.6 mm, Ea

Brand

Gemini

Part No

00F-4435-E0

Phase Name

C18

Elution Type

Isocratic

Mobile Phase

A: Water

B: Methanol

C: Glacial Acetic acid

Gradient Profile

Step No.

Time(min)

%A

%B

1

0

59

39.5

Flow Rate

1.00 mL/min

Temperature

25°C

Detection

UV-Vis Abs.-Variable Wave.(UV) @ (25°C)

Detection Info

Sample Notes

Mobile phase is waterglacial acetic acid (60:40:1.5) per USP