Carvedilol on Lux 5µm Cellulose-4 by SFC
LC Conditions
Column
Lux 5 µm Cellulose-4, LC Column 250 x 4.6 mm, Ea
Brand
Lux
Part No
00G-4491-E0
Phase Name
Cellulose-4
Elution Type
Isocratic
Mobile Phase
A: CO2/(Methanol + 0.1% IPA + 0.1% TFA) 80:20 (v/v)
Gradient Profile
Step No.
Time(min)
%A
%B
1
0
100
0
Flow Rate
3.00 mL/min
Temperature
30°C
Detection
UV-Vis Abs.-Diode Array (PDA) @ (30°C)
Detection Info
Sample Notes
Courtesy of Katrijn De Klerck, Debby Mangelings and Yvan Vander Heyden, Department of Analytical Chemistry and Pharmaceutical Technology, Vrije Universiteit Brussel, Brussels, Belgium. Results of this analysis yielded: Alpha >1.1 and Resolution >1.5 SecurityGuard™ Guard Cartridge System extends column lifetime. - SecurityGuard Cartridges, Lux Cellulose-4, 4 x 3.0mm ID, 10/Pk Part No.: AJ0-8627 - Holder Part No.: KJ0-4282
Order Items Used in This Application
- 1. Carvedilol
- 2. Carvedilol
-OEChem-06211003142D<br><br> 56 59 0 1 0 0 0 0 0999 V2000<br> 5.3923 2.3984 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.7524 0.5036 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.0743 -3.4472 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.1133 -3.8403 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5274 5.6694 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.0733 -0.9981 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.0274 4.1306 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.0274 4.1306 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.3364 5.0816 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7183 5.0816 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.7123 3.3458 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.7328 0.7002 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0<br> 6.0528 1.6476 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3933 -0.0507 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3518 5.3139 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.3424 3.3458 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.7328 3.5546 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.7029 5.3139 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.0547 4.5452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.7338 -1.7489 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3219 3.5546 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 4.5452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.4138 -2.6963 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.7543 -4.3946 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.7739 -4.5912 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.4148 -5.1454 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4538 -5.5386 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.0948 -6.0928 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.1143 -6.2894 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.1329 -4.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.3233 1.1657 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5274 6.2894 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.5968 1.3502 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.4402 2.1317 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.9374 -0.3480 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.7807 0.4335 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.5365 5.9057 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.5408 2.7584 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1459 3.0922 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.5182 5.9057 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4654 -1.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.6607 4.6764 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.2778 -2.0463 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1212 -1.2648 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.9088 3.0922 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.3940 4.6764 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.8698 -2.3990 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.0265 -3.1804 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5540 -0.0838 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0227 -5.0235 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.8460 -5.6605 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.5043 -6.5584 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.9159 -6.8768 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.0110 -3.4290 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.5250 -4.1588 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2547 -4.6448 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1 11 1 0 0 0 0<br> 1 13 1 0 0 0 0<br> 2 12 1 0 0 0 0<br> 2 49 1 0 0 0 0<br> 3 23 1 0 0 0 0<br> 3 24 1 0 0 0 0<br> 4 25 1 0 0 0 0<br> 4 30 1 0 0 0 0<br> 5 9 1 0 0 0 0<br> 5 10 1 0 0 0 0<br> 5 32 1 0 0 0 0<br> 6 14 1 0 0 0 0<br> 6 20 1 0 0 0 0<br> 6 41 1 0 0 0 0<br> 7 8 1 0 0 0 0<br> 7 9 2 0 0 0 0<br> 7 11 1 0 0 0 0<br> 8 10 1 0 0 0 0<br> 8 16 2 0 0 0 0<br> 9 15 1 0 0 0 0<br> 10 18 2 0 0 0 0<br> 11 17 2 0 0 0 0<br> 12 13 1 0 0 0 0<br> 12 14 1 0 0 0 0<br> 12 31 1 0 0 0 0<br> 13 33 1 0 0 0 0<br> 13 34 1 0 0 0 0<br> 14 35 1 0 0 0 0<br> 14 36 1 0 0 0 0<br> 15 19 2 0 0 0 0<br> 15 37 1 0 0 0 0<br> 16 21 1 0 0 0 0<br> 16 38 1 0 0 0 0<br> 17 19 1 0 0 0 0<br> 17 39 1 0 0 0 0<br> 18 22 1 0 0 0 0<br> 18 40 1 0 0 0 0<br> 19 42 1 0 0 0 0<br> 20 23 1 0 0 0 0<br> 20 43 1 0 0 0 0<br> 20 44 1 0 0 0 0<br> 21 22 2 0 0 0 0<br> 21 45 1 0 0 0 0<br> 22 46 1 0 0 0 0<br> 23 47 1 0 0 0 0<br> 23 48 1 0 0 0 0<br> 24 25 1 0 0 0 0<br> 24 26 2 0 0 0 0<br> 25 27 2 0 0 0 0<br> 26 28 1 0 0 0 0<br> 26 50 1 0 0 0 0<br> 27 29 1 0 0 0 0<br> 27 51 1 0 0 0 0<br> 28 29 2 0 0 0 0<br> 28 52 1 0 0 0 0<br> 29 53 1 0 0 0 0<br> 30 54 1 0 0 0 0<br> 30 55 1 0 0 0 0<br> 30 56 1 0 0 0 0<br>M END
Compound Name
Carvedilol
CID
2585
Molecular Formula
C24H26N2O4
Molecular Weight
406
No. Hydrogen Bond Acceptors
5
No. Hydrogen Bond Donors
3
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