Ibuprofen Dissolution - Kinetex 2.6 µm C18 75 x 4.6 mm
LC Conditions
Column
Kinetex 2.6 µm C18 100 Å, LC Column 75 x 4.6 mm, Ea
Brand
Kinetex
Part No
00C-4462-E0
Phase Name
C18
Elution Type
Isocratic
Mobile Phase
A: 40:60 4.0 g chloroactetic acid in water, pH3: ACN
Gradient Profile
Step No.
Time(min)
%A
%B
1
4
100
Flow Rate
1.80 mL/min
Temperature
21°C
System
Agilent Technologies 1100 Series Agilent Technologies 1100 Series
Detection
LC/UV (DAD, PDA) @ 254 nm (nanometers)
Detection Info
Sample Notes
Dissolution medium, 0.05 M phosphate buffer pH 7.2
Order Items Used in This Application
- 1. Ibuprofen
-OEChem-06211003152D<br><br> 33 33 0 1 0 0 0 0 0999 V2000<br> 4.5981 3.3450 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 1.8450 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -2.6550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -2.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -1.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 0.8450 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 1.8450 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0<br> 2.8660 -3.6550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -2.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -0.6550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 -0.6550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 0.3450 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 0.3450 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 2.3450 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 2.3450 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -2.0350 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.9441 -2.7376 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.3426 -2.0473 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 2.6950 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.2460 -3.6550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -4.2750 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.4860 -3.6550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3100 -1.6181 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.4631 -1.8450 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.6900 -2.6919 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3291 -0.9650 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.1350 -0.9650 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3291 0.6550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.1350 0.6550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.1760 2.8819 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3291 2.6550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.5560 1.8081 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.1350 3.6550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1 15 1 0 0 0 0<br> 1 33 1 0 0 0 0<br> 2 15 2 0 0 0 0<br> 3 4 1 0 0 0 0<br> 3 8 1 0 0 0 0<br> 3 9 1 0 0 0 0<br> 3 16 1 0 0 0 0<br> 4 5 1 0 0 0 0<br> 4 17 1 0 0 0 0<br> 4 18 1 0 0 0 0<br> 5 10 2 0 0 0 0<br> 5 11 1 0 0 0 0<br> 6 7 1 0 0 0 0<br> 6 12 2 0 0 0 0<br> 6 13 1 0 0 0 0<br> 7 14 1 0 0 0 0<br> 7 15 1 0 0 0 0<br> 7 19 1 0 0 0 0<br> 8 20 1 0 0 0 0<br> 8 21 1 0 0 0 0<br> 8 22 1 0 0 0 0<br> 9 23 1 0 0 0 0<br> 9 24 1 0 0 0 0<br> 9 25 1 0 0 0 0<br> 10 12 1 0 0 0 0<br> 10 26 1 0 0 0 0<br> 11 13 2 0 0 0 0<br> 11 27 1 0 0 0 0<br> 12 28 1 0 0 0 0<br> 13 29 1 0 0 0 0<br> 14 30 1 0 0 0 0<br> 14 31 1 0 0 0 0<br> 14 32 1 0 0 0 0<br>M END
Compound Name
Ibuprofen
CID
3672
Molecular Formula
C13H18O2
Molecular Weight
206
No. Hydrogen Bond Acceptors
2
No. Hydrogen Bond Donors
1
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