Lorazepam Tablets - USP Method
LC Conditions
Official Method
USP L01
Column
Luna 5 µm C18(2) 100 Å, LC Column 250 x 4.6 mm, Ea
Brand
Luna
Part No
00G-4252-E0
Phase Name
C18(2)
Elution Type
Isocratic
Mobile Phase
A: Water
B: Methanol
C: Acetic acid
Gradient Profile
Step No.
Time(min)
%A
%B
1
0
54
44
Flow Rate
2.00 mL/min
Temperature
22°C
Detection
UV-Vis Abs.-Variable Wave.(UV) @ (22°C)
Detection Info
Sample Notes
SecurityGuard™ Guard Cartridge System extends column lifetime. - SecurityGuard Cartridges, C18 4 x 3.0mm, 10/Pk Part No.: AJ0-4287 - Holder Part No.: KJ0-4282
Order Items Used in This Application
- 1. Lorazepam
-OEChem-06211003152D<br><br> 31 33 0 1 0 0 0 0 0999 V2000<br> 8.1647 -0.1360 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.6300 0.5528 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3100 -1.1602 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.1204 -2.8430 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.7188 -2.2836 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7439 -0.2592 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.5006 -0.6602 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.7188 -0.0367 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.5006 -1.6602 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.9413 0.9383 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.3100 -1.1602 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0<br> 6.3946 -0.1255 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7439 -2.0611 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3946 -2.1948 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.3006 -0.6393 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.3006 -1.6810 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.8969 1.2330 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2083 1.6184 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.1194 2.2079 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.4308 2.5934 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.3864 2.8881 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.9801 -0.6352 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.8568 -2.8881 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3874 0.4945 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3874 -2.8148 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.8364 -1.9930 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.6158 1.4357 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.7119 2.3907 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.9763 3.0151 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.5243 3.4926 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -0.6232 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1 15 1 0 0 0 0<br> 2 17 1 0 0 0 0<br> 3 11 1 0 0 0 0<br> 3 31 1 0 0 0 0<br> 4 13 2 0 0 0 0<br> 5 9 1 0 0 0 0<br> 5 13 1 0 0 0 0<br> 5 23 1 0 0 0 0<br> 6 8 2 0 0 0 0<br> 6 11 1 0 0 0 0<br> 7 8 1 0 0 0 0<br> 7 9 2 0 0 0 0<br> 7 12 1 0 0 0 0<br> 8 10 1 0 0 0 0<br> 9 14 1 0 0 0 0<br> 10 17 1 0 0 0 0<br> 10 18 2 0 0 0 0<br> 11 13 1 0 0 0 0<br> 11 22 1 0 0 0 0<br> 12 15 2 0 0 0 0<br> 12 24 1 0 0 0 0<br> 14 16 2 0 0 0 0<br> 14 25 1 0 0 0 0<br> 15 16 1 0 0 0 0<br> 16 26 1 0 0 0 0<br> 17 19 2 0 0 0 0<br> 18 20 1 0 0 0 0<br> 18 27 1 0 0 0 0<br> 19 21 1 0 0 0 0<br> 19 28 1 0 0 0 0<br> 20 21 2 0 0 0 0<br> 20 29 1 0 0 0 0<br> 21 30 1 0 0 0 0<br>M END
Compound Name
Lorazepam
CID
3958
Molecular Formula
C15H10Cl2N2O2
Molecular Weight
321
No. Hydrogen Bond Acceptors
3
No. Hydrogen Bond Donors
2
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