Lopinavir & Ritonavir Tablets USP (COVID-19) Luna 3 µm C8(2) 150 x 4.6 mm
LC Conditions
Column
Luna 3 µm C8(2) 100 Å, LC Column 150 x 4.6 mm, Ea
Brand
Luna
Part No
00F-4248-E0
Phase Name
C8(2)
Elution Type
Gradient
Mobile Phase
A: (175:100:100:625) of ACNTHF:Buffer (4.1 g/L of monobasic potassium phosphate in water)
Gradient Profile
Step No.
Time(min)
%A
%B
1
0
100
2
90
100
Flow Rate
1.50 mL/min
Temperature
40°C
System
Agilent Technologies 1260 Infinity Hybrid SFC/UHPLC Agilent Technologies 1260 Infinity
Detection
LC/UV (DAD, PDA) @ 215 nm (nanometers)
Detection Info
Sample Notes
Buffer = 4.1 g Potassium Phosphate monobasic in 1 L of Water Solution A = 50:50 ACN:Buffer Samples were dissolved and diluted in Solution A
Order Items Used in This Application
- 1. Ritonavir
- 2. Lopinavir
-OEChem-05111000492D<br><br> 98101 0 1 0 0 0 0 0999 V2000<br> 12.6090 0.0476 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.9757 -1.3433 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 0.2500 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 0.2500 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 -1.7500 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 -0.2500 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.9282 2.7500 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 1.7500 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 -1.7500 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0622 1.2500 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.7942 1.2500 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 12.4398 1.6567 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.1448 -2.9524 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 1.2500 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 4.5981 0.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -0.2500 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0<br> 3.7320 -1.2500 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 3.7320 1.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -1.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1962 1.7500 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0<br> 7.1962 2.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 1.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 2.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -2.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0622 3.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3301 3.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 3.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 3.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 -1.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -3.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -3.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.9282 1.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 4.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 4.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -4.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -4.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 4.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -4.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 10.6603 1.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.7942 0.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1962 -1.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 11.5263 1.2500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0622 -1.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 13.1090 0.9136 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 11.6308 0.2555 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 14.1035 1.0181 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 14.6913 0.2091 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 14.5102 1.9317 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.1667 -2.7445 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.6448 -2.0864 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 1.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.8101 -0.3326 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.2087 0.3577 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 0.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -1.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.1215 1.8577 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.5200 1.1674 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.6540 -1.1674 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.2554 -1.8577 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4641 2.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.7331 2.0600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.6592 2.4400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 -2.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 0.8700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0622 0.6300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.3722 2.7131 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.5991 3.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.7522 3.7869 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.6401 3.7869 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.7932 3.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.0201 2.7131 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3291 2.9400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.1350 2.9400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2690 -2.9400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.4631 -2.9400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3291 4.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.1350 4.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2690 -4.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.4631 -4.5600 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 5.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -5.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 11.0588 2.2250 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 10.2617 2.2250 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.1742 0.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 9.7942 -0.3700 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 10.4142 0.2500 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.5947 -0.7751 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.7976 -0.7751 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 14.7201 1.0829 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 11.1701 -0.1594 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 14.1897 -0.1553 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 15.0557 -0.2925 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 15.1929 0.5735 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 15.0766 1.6795 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 14.7624 2.4981 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 13.9438 2.1838 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.7060 -3.1594 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 10.2615 -2.0216 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1 44 1 0 0 0 0<br> 1 45 1 0 0 0 0<br> 2 43 1 0 0 0 0<br> 2 50 1 0 0 0 0<br> 16 3 1 1 0 0 0<br> 3 64 1 0 0 0 0<br> 4 22 2 0 0 0 0<br> 5 29 1 0 0 0 0<br> 5 41 1 0 0 0 0<br> 6 29 2 0 0 0 0<br> 7 32 2 0 0 0 0<br> 14 8 1 6 0 0 0<br> 8 22 1 0 0 0 0<br> 8 60 1 0 0 0 0<br> 17 9 1 1 0 0 0<br> 9 29 1 0 0 0 0<br> 9 63 1 0 0 0 0<br> 20 10 1 6 0 0 0<br> 10 32 1 0 0 0 0<br> 10 65 1 0 0 0 0<br> 11 32 1 0 0 0 0<br> 11 39 1 0 0 0 0<br> 11 40 1 0 0 0 0<br> 12 42 1 0 0 0 0<br> 12 44 2 0 0 0 0<br> 13 49 1 0 0 0 0<br> 13 50 2 0 0 0 0<br> 14 15 1 0 0 0 0<br> 14 18 1 0 0 0 0<br> 14 51 1 0 0 0 0<br> 15 16 1 0 0 0 0<br> 15 52 1 0 0 0 0<br> 15 53 1 0 0 0 0<br> 16 17 1 0 0 0 0<br> 16 54 1 0 0 0 0<br> 17 19 1 0 0 0 0<br> 17 55 1 0 0 0 0<br> 18 23 1 0 0 0 0<br> 18 56 1 0 0 0 0<br> 18 57 1 0 0 0 0<br> 19 24 1 0 0 0 0<br> 19 58 1 0 0 0 0<br> 19 59 1 0 0 0 0<br> 20 21 1 0 0 0 0<br> 20 22 1 0 0 0 0<br> 20 61 1 0 0 0 0<br> 21 25 1 0 0 0 0<br> 21 26 1 0 0 0 0<br> 21 62 1 0 0 0 0<br> 23 27 2 0 0 0 0<br> 23 28 1 0 0 0 0<br> 24 30 2 0 0 0 0<br> 24 31 1 0 0 0 0<br> 25 66 1 0 0 0 0<br> 25 67 1 0 0 0 0<br> 25 68 1 0 0 0 0<br> 26 69 1 0 0 0 0<br> 26 70 1 0 0 0 0<br> 26 71 1 0 0 0 0<br> 27 33 1 0 0 0 0<br> 27 72 1 0 0 0 0<br> 28 34 2 0 0 0 0<br> 28 73 1 0 0 0 0<br> 30 35 1 0 0 0 0<br> 30 74 1 0 0 0 0<br> 31 36 2 0 0 0 0<br> 31 75 1 0 0 0 0<br> 33 37 2 0 0 0 0<br> 33 76 1 0 0 0 0<br> 34 37 1 0 0 0 0<br> 34 77 1 0 0 0 0<br> 35 38 2 0 0 0 0<br> 35 78 1 0 0 0 0<br> 36 38 1 0 0 0 0<br> 36 79 1 0 0 0 0<br> 37 80 1 0 0 0 0<br> 38 81 1 0 0 0 0<br> 39 42 1 0 0 0 0<br> 39 82 1 0 0 0 0<br> 39 83 1 0 0 0 0<br> 40 84 1 0 0 0 0<br> 40 85 1 0 0 0 0<br> 40 86 1 0 0 0 0<br> 41 43 1 0 0 0 0<br> 41 87 1 0 0 0 0<br> 41 88 1 0 0 0 0<br> 42 45 2 0 0 0 0<br> 43 49 2 0 0 0 0<br> 44 46 1 0 0 0 0<br> 45 90 1 0 0 0 0<br> 46 47 1 0 0 0 0<br> 46 48 1 0 0 0 0<br> 46 89 1 0 0 0 0<br> 47 91 1 0 0 0 0<br> 47 92 1 0 0 0 0<br> 47 93 1 0 0 0 0<br> 48 94 1 0 0 0 0<br> 48 95 1 0 0 0 0<br> 48 96 1 0 0 0 0<br> 49 97 1 0 0 0 0<br> 50 98 1 0 0 0 0<br>M END
Compound Name
Ritonavir
CID
392622
Molecular Formula
C37H48N6O5S2
Molecular Weight
720
No. Hydrogen Bond Acceptors
7
No. Hydrogen Bond Donors
4
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