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Quantitative Analysis of Gamma-Hydroxybutyrate (GHB) in Whole Blood Using Fast SPE and LC-MS/MS (TN-1260)
Testing for GHB can be difficult due to inaccurate/unreliable response in immunoassays or chromatographic screens and due to the stability of the compound. The time sensitive nature of this assay demands for an analytical procedure that is quick, efficient, and one that preserves the authenticity of the biological specimen. The goal of this application is to present a comprehensive method for the quantitation of GHB in human blood using solid phase extraction (SPE) in conjunction with LC-MS/MS analysis.
Quantitative Analysis of Gamma-Hydroxybutyrate (GHB) in Whole Blood Using Fast SPE and LC-MS/MS (TN-1260)
Testing for GHB can be difficult due to inaccurate/unreliable response in immunoassays or chromatographic screens and due to the stability of the compound. The time sensitive nature of this assay demands for an analytical procedure that is quick, efficient, and one that preserves the authenticity of the biological specimen. The goal of this application is to present a comprehensive method for the quantitation of GHB in human blood using solid phase extraction (SPE) in conjunction with LC-MS/MS analysis.
Document Type:
Technical Notes
Target Industries:
Brands:
Separation Modes:
HILIC, Reversed Phase, Solid Phase Extraction
Phases:
Quantitative Analysis of Gamma-Hydroxybutyrate (GHB) in Whole Blood Using Fast SPE and LC-MS/MS (TN-1260)
Testing for GHB can be difficult due to inaccurate/unreliable response in immunoassays or chromatographic screens and due to the stability of the compound. The time sensitive nature of this assay demands for an analytical procedure that is quick, efficient, and one that preserves the authenticity of the biological specimen. The goal of this application is to present a comprehensive method for the quantitation of GHB in human blood using solid phase extraction (SPE) in conjunction with LC-MS/MS analysis.
| Target Industries: | Clinical Research, Forensic Toxicology |
| Techniques: | HILIC Chromatography, HPLC Reversed Phase, Solid Phase Extraction |
| Brands: | Strata-X Pro |
| Separation Modes: | HILIC, Reversed Phase, Solid Phase Extraction |
| Phases: | Kinetex C18, Luna HILIC |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.