Screening Approach for the Separation of Pharmaceutical Compounds using Lux Polysaccharide-Based Chiral Stationary Phases in SFC Mode (TN-9004)

In this technical note, we present various SFC screening approaches for the chiral separation of a 56-pharmaceutical compound test set using Lux polysaccharide-based chiral stationary phases. The new Lux Amylose-1 provides the largest number of baseline separations. Additional generic chiral separation strategies for SFC are highlighted for increasing success rates.

Document Type:

Technical Notes

Target Industries:

Biopharmaceutical Analysis, Pharmaceutical

Techniques:

HPLC, HPLC-Chiral, SFC

Brands:

Axia, Lux, SecurityGuard

Separation Modes:

Chiral

Phases:

Lux Amylose-1, Lux Cellulose-1, Lux Cellulose-2, Lux Cellulose-3 , Lux Cellulose-4