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Limit of Free Salicylic Acid in Aspirin Tablets Using the Kinetex 5 µm C18 Under USP Allowable Adjustments
A robust separation of Aspirin (Acetylsalicylic Acid) and related impurity Salicylic Acid under the USP conditions. The application demonstrates the potential method improvements that can be achieved per the allowable adjustments outlined in USP General Chapter <621> relative to the original column and conditions referenced in the monograph.
Limit of Free Salicylic Acid in Aspirin Tablets Using the Kinetex 5 µm C18 Under USP Allowable Adjustments
A robust separation of Aspirin (Acetylsalicylic Acid) and related impurity Salicylic Acid under the USP conditions. The application demonstrates the potential method improvements that can be achieved per the allowable adjustments outlined in USP General Chapter <621> relative to the original column and conditions referenced in the monograph.
Document Type:
Technical Notes
Target Industries:
Pharmaceutical
Techniques:
HPLC
Brands:
Kinetex
Separation Modes:
Reversed Phase
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