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This user guide provides step-by-step instructions for using Clarity RP-Desalting tubes and 96-well plates to efficiently remove salts, reagents, and synthesis byproducts from trityl-off oligos. Designed for reversed-phase desalting, this method enhances sample purity (~70%) while maintaining high throughput. By leveraging hydrophobic interactions and ion-pairing agents, Clarity RP-Desalting ensures reliable purification, delivering oligonucleotides in a small, concentrated volume ideal for structural analysis and downstream applications.
Clarity RP-Desalting Tubes and 96-Well Plates
This user guide provides step-by-step instructions for using Clarity RP-Desalting tubes and 96-well plates to efficiently remove salts, reagents, and synthesis byproducts from trityl-off oligos. Designed for reversed-phase desalting, this method enhances sample purity (~70%) while maintaining high throughput. By leveraging hydrophobic interactions and ion-pairing agents, Clarity RP-Desalting ensures reliable purification, delivering oligonucleotides in a small, concentrated volume ideal for structural analysis and downstream applications.
This user guide provides step-by-step instructions for using Clarity RP-Desalting tubes and 96-well plates to efficiently remove salts, reagents, and synthesis byproducts from trityl-off oligos. Designed for reversed-phase desalting, this method enhances sample purity (~70%) while maintaining high throughput. By leveraging hydrophobic interactions and ion-pairing agents, Clarity RP-Desalting ensures reliable purification, delivering oligonucleotides in a small, concentrated volume ideal for structural analysis and downstream applications.