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LC/MS-MS Analysis of Benzodiazepines in Urine with One-Step Clean Up Using B-Gone (TN-1383)
This technical note details the quantitation of benzodiazepines in urine using 30-minute room temperature hydrolysis with Kura B-One; and one-step cleanup with Beta-Gone. Combined with fast LC-MS/MS analysis using a Kinetex phenyl hexyl LC column on the SCIEX® 5500 system, this efficient workflow delivers clean samples, high recovery, and accurate results in a simple and reliable method.
LC/MS-MS Analysis of Benzodiazepines in Urine with One-Step Clean Up Using B-Gone (TN-1383)
This technical note details the quantitation of benzodiazepines in urine using 30-minute room temperature hydrolysis with Kura B-One; and one-step cleanup with Beta-Gone. Combined with fast LC-MS/MS analysis using a Kinetex phenyl hexyl LC column on the SCIEX® 5500 system, this efficient workflow delivers clean samples, high recovery, and accurate results in a simple and reliable method.
Document Type:
Technical Notes
Target Industries:
Techniques:
Separation Modes:
Reversed Phase
Phases:
LC/MS-MS Analysis of Benzodiazepines in Urine with One-Step Clean Up Using B-Gone (TN-1383)
This technical note details the quantitation of benzodiazepines in urine using 30-minute room temperature hydrolysis with Kura B-One; and one-step cleanup with Beta-Gone. Combined with fast LC-MS/MS analysis using a Kinetex phenyl hexyl LC column on the SCIEX® 5500 system, this efficient workflow delivers clean samples, high recovery, and accurate results in a simple and reliable method.
| Target Industries: | Forensic Toxicology |
| Techniques: | HPLC, HPLC Reversed Phase, Sample Preparation |
| Brands: | Beta-Gone, Kinetex |
| Separation Modes: | Reversed Phase |
| Phases: | Kinetex Phenyl-Hexyl |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.