SPE Knowledge Center
What is Sample Preparation Extraction?
Fundamental Tips
Solid Phase Extraction (SPE) Method Development: A Practical Overview article
Generic SPE Method by Retention Mechanism article
How is normal phase SPE different from reversed phase SPE? How do I decide which one to use? article
VIDEO Are you using the right SPE wash step?video
What is the Matrix Effect? article
Why Is It Necessary to Dry the SPE Sorbent Before Elution? article
NEW: VIDEO What is magnetic bead-based protein purification? video
Application
Considerations when working with solid samples and SPE article
Sample Pre-treatment Procedures for Bioanalytical Samples article
Peptide Mapping Sample Prep - Good Practices for Tryptic Digests article
Sample Preparation for Oligonucleotides article
Why Remove Phospholipids From a Sample? article
Video How to improve my oligonucleotide conjugate recovery with Clarity OTX Pro video
Troubleshooting Tips
Over-Drying of Silica-Based SPE Cartridges Can Lead to Poor Sample Recovery article
Troubleshooting SPE article
I am getting low recovery in my SPE method, how do I fix the problem? article
VIDEO My recovery is lower than expected after my SPE method. Why and how can I fix it? video
Why are my recoveries greater than 100%? article
VIDEO My Sample Won’t Flow Through My SPE Cartridge, Why Is This Happening? video
SPE Troubleshooting - Extra Peak article