Core-Shell Technology
Phenomenex proudly offers a wide range of cutting-edge core-shell products that have revolutionized chromatography. Our core-shell columns deliver unmatched performance and efficiency, aiding scientists and researchers in achieving superior analytical results. These columns are compatible with various sample matrices and mobile phases, making them versatile for different analytical methods.
Choosing our core-shell columns can greatly enhance your analytical performance, saving time and resources while achieving superior separation and detection. Whether you're analyzing small molecules, peptides, proteins, or complex mixtures, our products deliver reliable and reproducible results. We design, manufacture, and sell our own silica and organo-silica core-shell particles, ensuring the highest quality and performance for your chromatographic needs.
Unlock new possibilities with our advanced core-shell technology
Kinetex Columns
Versatile core-shell technology with 11 diverse phases and 5 particle sizes, delivering extremely high efficiencies due to reduced band broadening.
Aeris Columns
Core Shell Technology for proteins and peptides.
Biozen Biologics Columns
Core-shell phases with bioInert hardware to improve sensitivity and chromatographic performance for biologics analysis.
Applications of Core-Shell Technology
Core-shell technology represents a significant advancement in analytical chemistry and due to these advantages has found applications across multiple industries. Pharmaceutical, food safety, clinical research, environmental, regulatory and research labs all benefit from implementing core-shell technology into their laboratories.
Explore some of our popular core-shell applications
What is Core-Shell?
Core-shell represents a groundbreaking technique that has transformed chromatography. This advanced technology employs particles with a solid core enveloped by a porous shell, resulting in enhanced separation efficiency, allowing for increased sample throughput or higher resolution separation of complex mixtures.
Core-shell technology is a state-of-the-art approach to producing high-performance stationary phases for U/HPLC. It involves creating structures where a solid silica core is encased by a thin porous shell layer. This innovative design presents numerous advantages over traditional particle structures, making it highly valuable in many applications.
The formation of core-shell structures occurs through a process known as shell deposition. In this process, a precursor material is meticulously coated onto the solid core particles' surface. The precursor material then transforms, forming a thin, uniform shell layer around the core. The shell layer's thickness can be precisely controlled, allowing for customization based on specific needs.
Core-shell technology offers several significant benefits:
- Enhanced Efficiency: The unique structure of core-shell particles allows for superior separation and improved analytical performance. The shell layer's controlled porosity provides faster analysis times and better resolution.
- Improved Sensitivity: The shell layer minimizes diffusion of the analyte bands, making the peaks narrower and therefore taller. This leads to more accurate and reliable analytical results.
- Versatility: Core-shell particles are compatible with various sample matrices and mobile phases, making them suitable for different analytical methods.
- Customization: The shell layer's thickness can be precisely controlled, allowing for tailored properties based on specific needs.
Phenomenex leads in core-shell technology, offering a range of innovative products tailored to meet the diverse needs of scientists and researchers. Our core-shell particles deliver outstanding performance, providing increased efficiency and sensitivity for various applications.
