Strata-Mag RP Magnetic Beads Extraction
Strata-Mag RP transforms reversed-phase extraction, utilizing magnetic bead technology to deliver reproducible results at lower cost with seamless integration into automated platforms. SPE challenges like channeling and plugging are eliminated. Clinical research laboratories can now transition to fully automated sample preparation to achieve higher throughput and greater efficiency with consistent, reliable extraction performance.
- Seamless integration into automated sample preparation
- Reproducible results and high throughput
- Greater efficiency with consistent, reliable extraction at lower cost per sample
Order
Overview
Key Application and Benefit Highlights
Manual Workflow
Ideal for:
- Method development
- Low-to medium-throughput testing
- Laboratories with limited automation capabilities
Automated Workflow
Ideal for:
- Routine LC-MS/MS testing
- Increased efficiency and higher throughput
- Fully automated sample preparation
Say goodbye to channeling, plugging, and SPE bottlenecks.
Laboratories seeking flexibility and reliable extraction performance while transitioning seamlessly from low-volume processing to fully automated operation can rely on Strata-Mag RP for consistency and scalability.
Which workflow is the best for your lab?
Manual Extraction Workflow
- Operator manually performs all liquid-handling steps.
- Magnetic beads remain in the same well during bind, wash, and elution steps.
- Magnetic rack retains the beads while liquids are removed and replaced
- Same Strata-Mag RP extraction chemistry
Semi Automated Extraction Workflow (KingFisher)
- Sample and reagents are prepared and pre-filled before the run
- Magnetic head moves the beads through bind, wash, and elution solutions
- Reduces manual liquid handling during the extraction run
- Same Strata-Mag RP extraction chemistry
Automated Extraction Workflow (Beckman Biomek)
- Liquid handler automates reagent addition and liquid removal
- Magnetic beads remain in the same well during bind, wash, and elution steps.
- Minimizes operator intervention during the extraction workflow
- Same Strata-Mag RP extraction chemistry
Comparison Between Manual and Automated Methods for rT3 Analysis in Human Serum
Frequently Asked Questions About Strata-Mag RP
What is Strata-Mag RP?
Strata-Mag RP is a reversed-phase magnetic bead sample preparation technology designed for LC-MS workflows. It combines the selectivity of reversed-phase extraction with the simplicity of magnetic separation, enabling efficient sample cleanup and easy integration with automated laboratory workflows. It is particularly well suited for hydrophobic and weakly polar analytes commonly measured in clinical laboratories.
Which clinical applications is Strata-Mag RP best suited for?
Strata-Mag RP is optimized for clinical LC-MS applications involving hydrophobic analytes, including reverse triiodothyronine (rT3), steroid hormones. These assays often demand effective matrix cleanup, high reproducibility, and scalable workflows to support growing testing volumes in clinical laboratories.
How does Strata-Mag RP compare with traditional SPE?
Unlike traditional SPE methods that rely on vacuum manifolds or positive-pressure systems, Strata-Mag RP uses magnetic separation to simplify extraction workflows. This can reduce hands-on time, minimize solvent consumption, eliminate flow-rate variability, and make automation easier while maintaining the sample cleanliness and performance expected from chromatography-based extraction methods.
Can Strata-Mag RP be automated?
Yes. Strata-Mag RP was developed with automation compatibility in mind. The magnetic separation workflow can be incorporated into manual, semi-automated, or fully automated sample preparation platforms, helping laboratories increase throughput while reducing operator-to-operator variability.
What benefits does Strata-Mag RP provide to clinical laboratories?
Strata-Mag RP helps clinical laboratories simplify sample preparation while improving operational efficiency. Key benefits include:
- Reduced hands-on processing time
- Improved workflow reproducibility
- Lower dependence on highly skilled operators
- Easy implementation on automated platforms
- Lower solvent and consumable usage
- Scalable processing for high-throughput testing environments
These advantages can help laboratories meet increasing sample volume demand for clinical assays while maintaining high data quality.