Strata-X-C SPE Products
Weak Anion Mixed-Mode Solid Phase Extraction (SPE)
A weak anion-exchange functionalized polymeric sorbent that allows for complete retention of acidic compounds with a pKa less than 5, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.
SP
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2134
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Overview
3 Mechanism of Retention
3
Strong Cation-Exchange
false
π-π Bonding
false
π-π Bonding
false
Available Formats
4
96-Well-Plate
false
96-Well-Plate
false
1, 3, and 6mL Tubes
false
Giga Tubes (12-150mL Tubes)
false
On-line Extraction Columns and Cartridges
false
Starting Method
For Bases with pKa ≤ 10.5
Column
1mL Methanol
Equilibrate
1 mL Acidified Water
Load
Diluted Acidified Sample
Wash 1
1 mL 0.1 N HCI in Water (collect this fraction to analyze Polar Neutrals)
Wash 2
1 mL 0.1 N HCI in Methanol (collect this fraction to analyze Neutrals/Acids)
Elute Bases
2x 500 µL 5 % NH4OH in Methanol
Elute Weak Acids
2x 500 µL 5 % Formic Acid in Methanol
Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.
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