Strata-XL-AW SPE Products
Large Particle Weak Anion Mixed-Mode Solid Phase Extraction (SPE)
A large particle, weak anion-exchange functionalized polymeric sorbent that allows for complete retention of acidic compounds with a pKa less than 5, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound. The large particle format makes this sorbent ideal for processing large volumes or viscous samples.
SP
292
2137
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Overview
3 Mechanism of Retention
4
Weak Anion-Exchange
false
π-π Bonding
false
Hydrophobic Interaction
false
Available Formats
4
96-Well-Plate
false
1, 3, and 6mL Tubes
false
Giga Tubes (12-150mL Tubes)
false
Starting Method
For Acids with pKa ≤ 5
Column
1mL Methanol
Equilibrate
1 mL Water, pH 6-7
Load
Diluted Sample pH 6-7
Wash 1
1 mL 25 mM Ammonium Acetate Buffered, pH 6-7
Wash 2
1 mL Methanol
Elute Acids
2x 500 µL 5 % NH4OH in Methanol
Elute Weak Acids
2x 500 µL 5 % Formic Acid in Methanol
Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.
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