Strata-XL-C SPE Products
Large Particle Strong Cation Mixed-Mode Solid Phase Extraction (SPE)
A strong cation-exchange functionalized polymeric sorbent that allows for complete retention of basic compounds with a pKa less than 10.5, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound. The large particle format is ideal for processing large volumes or viscous samples.
SP
292
2138
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Overview
3 Mechanism of Retention
4
Strong Cation-Exchange
false
π-π Bonding
false
Hydrophobic Interaction
false
Available Formats
4
96-Well-Plate
false
1, 3, and 6mL Tubes
false
Giga Tubes (12-150mL Tubes)
false
Starting Method
For Bases with pKa ≤ 10.5
Column
1mL Methanol
Equilibrate
1 mL Acidified Water
Load
Diluted Acidified Sample
Wash 1
1 mL 0.1 N HCI in Water (collect this fraction to analyze Polar Neutrals)
Wash 2
1 mL 0.1 N HCI in Methanol (collect this fraction to analyze Neutrals/Acids)
Elute Any Acids
2x 500 µL 5 % NH4OH in Methanol
Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.
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