Simvastatin by HPLC-Kinetex 2.6um XB-C18 150x4.6mm
LC Conditions
Column
Kinetex 2.6 µm XB-C18 100 Å, LC Column 150 x 4.6 mm, Ea
Brand
Kinetex
Part No
00F-4496-E0
Phase Name
XB-C18
Elution Type
Isocratic
Mobile Phase
A: 65:35 ACN:28mM sodium phosphate pH 4.5
Gradient Profile
Step No.
Time(min)
%A
%B
1
15
100
0
Flow Rate
1.50 mL/min
Temperature
0°C
Detection
UV-Vis Abs.-Diode Array (PDA) @ (22°C)
Detection Info
Order Items Used in This Application
- 1. Lovastatin
- 2. Simvastatin
-OEChem-05151001052D<br><br> 65 67 0 1 0 0 0 0 0999 V2000<br> 3.7320 0.5548 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.1893 -1.4997 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5740 -2.9695 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 0.5548 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 8.0379 -3.0096 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5981 2.0548 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0<br> 5.4920 1.5202 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 3.7320 1.5548 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 6.3981 2.0340 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 4.5981 3.0548 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4804 0.5202 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 2.0548 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 3.0548 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 3.7320 3.5548 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3406 0.0102 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3981 3.0756 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4920 3.5895 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.2622 1.5307 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3291 -0.9897 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 2.0000 3.5548 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4573 -1.4796 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4458 -2.4796 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 2.8660 0.0548 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.3060 -2.9896 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -0.9452 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0<br> 7.1777 -2.4996 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -1.4452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 -1.4452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -2.4452 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5915 1.2048 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.0259 1.2050 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2690 1.2448 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.9356 2.3430 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.8712 0.6349 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.2617 -0.0599 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.2554 2.1625 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.6540 1.4722 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 3.6748 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.7320 4.1748 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.9499 -0.1045 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.5594 0.5904 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.9338 3.3877 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.4848 4.2094 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.9501 0.9949 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.7979 1.2186 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 7.5742 2.0664 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.8696 -0.6859 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.3100 4.0918 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.4631 3.8648 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.6900 3.0179 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.2520 -0.8946 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.8455 -1.5802 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.9124 -2.1634 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 5.9020 -3.4599 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 6.6990 -3.4691 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.8660 -1.5652 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.7880 -0.8626 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.3894 -1.5528 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.5668 -3.5895 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 3.4220 -1.9821 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.2690 -1.7552 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 4.0420 -0.9082 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 1.3800 -2.4452 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.0000 -3.0652 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 2.6200 -2.4452 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0<br> 8 1 1 1 0 0 0<br> 1 23 1 0 0 0 0<br> 2 19 1 0 0 0 0<br> 2 26 1 0 0 0 0<br> 22 3 1 6 0 0 0<br> 3 59 1 0 0 0 0<br> 4 23 2 0 0 0 0<br> 5 26 2 0 0 0 0<br> 6 7 1 0 0 0 0<br> 6 8 1 0 0 0 0<br> 6 10 1 0 0 0 0<br> 6 30 1 6 0 0 0<br> 7 9 1 0 0 0 0<br> 7 11 1 6 0 0 0<br> 7 31 1 0 0 0 0<br> 8 12 1 0 0 0 0<br> 8 32 1 0 0 0 0<br> 9 16 1 0 0 0 0<br> 9 18 1 6 0 0 0<br> 9 33 1 0 0 0 0<br> 10 14 2 0 0 0 0<br> 10 17 1 0 0 0 0<br> 11 15 1 0 0 0 0<br> 11 34 1 0 0 0 0<br> 11 35 1 0 0 0 0<br> 12 13 1 0 0 0 0<br> 12 36 1 0 0 0 0<br> 12 37 1 0 0 0 0<br> 13 14 1 0 0 0 0<br> 13 20 1 1 0 0 0<br> 13 38 1 0 0 0 0<br> 14 39 1 0 0 0 0<br> 19 15 1 1 0 0 0<br> 15 40 1 0 0 0 0<br> 15 41 1 0 0 0 0<br> 16 17 2 0 0 0 0<br> 16 42 1 0 0 0 0<br> 17 43 1 0 0 0 0<br> 18 44 1 0 0 0 0<br> 18 45 1 0 0 0 0<br> 18 46 1 0 0 0 0<br> 19 21 1 0 0 0 0<br> 19 47 1 0 0 0 0<br> 20 48 1 0 0 0 0<br> 20 49 1 0 0 0 0<br> 20 50 1 0 0 0 0<br> 21 22 1 0 0 0 0<br> 21 51 1 0 0 0 0<br> 21 52 1 0 0 0 0<br> 22 24 1 0 0 0 0<br> 22 53 1 0 0 0 0<br> 23 25 1 0 0 0 0<br> 24 26 1 0 0 0 0<br> 24 54 1 0 0 0 0<br> 24 55 1 0 0 0 0<br> 25 27 1 0 0 0 0<br> 25 28 1 1 0 0 0<br> 25 56 1 0 0 0 0<br> 27 29 1 0 0 0 0<br> 27 57 1 0 0 0 0<br> 27 58 1 0 0 0 0<br> 28 60 1 0 0 0 0<br> 28 61 1 0 0 0 0<br> 28 62 1 0 0 0 0<br> 29 63 1 0 0 0 0<br> 29 64 1 0 0 0 0<br> 29 65 1 0 0 0 0<br>M END
Compound Name
Lovastatin
CID
53232
Molecular Formula
C24H36O5
Molecular Weight
404
No. Hydrogen Bond Acceptors
5
No. Hydrogen Bond Donors
1
Similar Applications
Reversed Phase
Statin drugs on a Kinetex 2.6 µm F5 50 x 2.1
Kinetex 2.6 µm F5 100 Å, LC Column 50 x 2.1 mm, Ea
22798
Reversed Phase
USP Simvastatin Lovastatin on Kinetex 2.6um C18 75x4.60mm using Shimadzu Nexera
Kinetex 2.6 µm C18 100 Å, LC Column 75 x 4.6 mm, Ea
19968
Reversed Phase
USP Simvastatin Lovastatin on Kinetex 2.6um C18 100x2.10mm using Shimadzu Nexera
Kinetex 2.6 µm C18 100 Å, LC Column 100 x 2.1 mm, Ea
19961
Reversed Phase
USP Simvastatin Lovastatin on Kinetex 2.6um C18 150x4.60mm using Shimadzu Nexera
Kinetex 2.6 µm C18 100 Å, LC Column 150 x 4.6 mm, Ea
19960