BioZen Peptide-XB-C18
Digested mAbs or ADCs typically include a large body of compounds which are crucial to understanding post translation modifications. So we designed our Biozen™ Peptide columns to offer highly useful and unique retention profiles. Biozen Peptide XB-C18 allows for fast and effective elution windows by utilizing core-shell particles to gain sharper peaks, better peak capacities, and overall higher sensitivity.
Biozen Peptide columns provide:
- Unique retention profiles
- Greater peak coverage
- High efficiency on both HPLC and UHPLC
Order
Overview
Inside bioZen BioTi Hardware
Conditions for both columns:
Sodium Sulfate, pH 5.0
Sample:
- γ-Globulin, 5 mg/mL
- Ovalbumin, 1 mg/mL
Peptide Mapping: Reversed Phase LC
Cetuximab Peptide Map
Anti Rituximab Fab Peptide Map
Gradient:
Time (min)
Conditions for both columns:
Gradient:
Time (min)
Sample:
As noted
TICs for Infliximab, XB-C18 vs. PS-C18
LC-UV conditions
Gradient:
Time (min)
Sample:
Infliximab Digest, 1 µg