Kinetex Core-Shell C18 HPLC Column
The Go-To Core-Shell Selectivity for Hydrophobic Compounds!
The well-rounded, all-purpose core-shell Kinetex C18 HPLC column produces high efficiencies compared to traditional, fully porous columns. HPLC C18 columns come in various configurations to ensure outstanding performance and are recognized as the most retentive among alkyl-bonded phases. When used with UHPLC systems, the 2.6 µm size achieves similar performance to fully porous sub-2 µm particles but at significantly lower backpressure. Yielding remarkable chromatographic resolution, higher peak capacities, and greater sensitivity, the Kinetex C18 columns maximize the efficiency of every HPLC or UHPLC analysis.
Advantages of Kinetex Core-Shell C18 HPLC Columns
- Compatible with all Analytical HPLC/UHPLC Systems*
- Four fully scalable particle sizes available
- Excellent Reproducibility and Batch-to-Batch Confidence
- USP: L1
*Kinetex C18 analytical columns are compatible with all LC systems with standard LC column end-fittings threaded in 10-32. Please contact us for any questions and information about fitting compatibility and any other column internal diameters.
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Overview
Compatibility
The Kinetex C18 column is fully compatible with all UHPLC instruments, ensuring seamless integration into any lab setup. This column is designed for easy installation and optimal performance. For installation, loosen the collet, place the tool between the gold compression screw and collet for quick release, adjust the tubing to the correct port depth, and connect the Kinetex column to the end-fitting. This universal compatibility allows you to leverage the powerful sub-2 µm column technology across different systems effortlessly.
Balances Retention and Performance
The Kinetex C18 column offers a well-balanced C18 phase that delivers the highest level of hydrophobic selectivity compared to other Kinetex phases
Upgrade from Traditional Fully Porous to Kinetex Core-Shell
Enhance your analytical method instantly by upgrading to the Kinetex C18 column for superior performance. Take advantage of the fully scalable available particle sizes of Kinetex C18 to bring improved performance to any LC system!
Core-shell columns are best suited for the rapid and precise separation of complex drug mixtures. Improve the quality control process with Kinetex Core-Shell columns.
1.7 µm Fully Porous vs. 1.7 µm Core-Shell
Conditions for all columns:
Sample:
1. Acetophenone
2. Benzene
3. Toluene
4. Naphthalene
Fully Porous vs. Core-Shell
◊ Signal-to-noise ratio of peak 2; ∆ Based on average peak widths; *Waters, ACQUITY, and UPLC are registered trademarks of Waters Corporation. Phenomenex is not affiliated with Waters Corporation. Comparative separations may not be representative of all applications. Conditions same for both columns except where noted.
Conditions for both columns:
Sample:
1. Procainamide
2. Acetaminophen
3. Folic acid
4. Sulfathiazole
5. Acebutolol
6. Dextromethorphan
7. Diphenhydramine
8. Propafenone
9. Amitriptyline
10. Fluoxetine
11. Naproxen
12. Diflunisal
13. Indomethacin
Performance with Kinetex C18 on HPLC and UHPLC Systems
Quickly improve the productivity and performance of your existing methods and utilize the core-shell advantage to deliver the performance you need at backpressures the system can handle.
Fully Porous vs. Core-Shell
*Agilent 1100 was optimized with the Core-Shell Performance Enhancement Kit AQ0-8892. Agilent and ZORBAX are registered trademarks of Agilent Technologies, Inc. Phenomenex is not affiliated with Agilent Technologies. Comparative separations may not be representative of all applications.
Sample:
Mupirocin degradants