SecurityGuard Column Protection
A common cause of high backpressure, split peaks, broad peaks, baseline noise, baseline drift, and loss of resolution is contaminants. All mobile phases contain some chemical contaminants or micro particulates, from the sample, solvent, or wear on the polymeric seals of the pump or injector. These contaminants can clog frits, irreversibly bind to columns, degrade performance, and even damage the flow cell. An easy solution, SecurityGuard is a universal column protection system designed to effectively (and inexpensively), protect your valuable columns, from the damaging effects of chemical contaminants, without altering your chromatographic results.
- Protects chromatographic results
- Extends UHPLC, HPLC, SFC, and PREP column lifetime
- Virtually no change in chromatography
- Simple to use
- Saves time and money
- Compatible with virtually all vendors columns
Removes Harmful Contaminants and Particulates
UHPLC
With SecurityGuard ULTRA
Without SecurityGuard ULTRA
HPLC
PREP
Protect Any Column
Compatible HPLC Fittings
Installing the SecurityGuard protection system into your favorite column is easy. The floating outlet from the SecurityGuard holder automatically adjusts to the precise depth of virtually every manufacturer’s column. This ensures a low dead volume, leak free connection, without the use of unions or adapters, no matter which manufacturer’s column you are using.
Longer Column Lifetimes
Keep Columns Performing Their Best
When contaminates and particulates build up at the head of the column or on the guard cartridges, system pressures dramatically increase. Simply replace the SecurityGuard cartridge instead of your column and you are able to regain normal operating conditions and reclaim original column performance.
Accelerated column lifetime test
SecurityGuard Standard Performance
Maintain Column Performance
Virtually No Change in Chromatography
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Columns:
Kinetex 1.7 µm XB-C18
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Dimension:
50 x 2.1 mm
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Mobile Phase:
Acetonitrile / Water (50:50)
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Flow Rate:
1 mL/min
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Temperature:
22 °C
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Injection Volume:
1 µL
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Detection:
UV @ 270 nm
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Sample:
1. Acetophenone
2. Benzene
3. Toluene
4. Naphthalene
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| No Guard | SecurityGuard ULTRA | Competitor | |
|---|---|---|---|
| Efficiency (p/m) | 11,795 | 11,390 | 8,591 |
| Symmetry | 0.92 | 0.86 |
0.69 |
| Selectivity | 1.47 | 1.46 | 1.46 |
| Backpressure (bar) | 354 | 384 | 384 |
Protection without altering your results!
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Columns:
Luna® 3 μm C18(2)
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Dimension:
150 x 4.6 mm
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Part No.:
00F-4251-E0
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Mobile Phase:
Acetonitrile / Water (65:35)
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Flow Rate:
0.75 mL/min
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Temperature:
25 °C
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Injection Volume:
0.5 µL
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Detection:
UV @ 254 nm
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Sample:
1. Uracil
2. Acetophenone
3. Toluene
4. Naphthalene
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PREP HPLC Column Protection
Protect Your Purification Results
The SecurityGuard PREP system was designed to effectively and inexpensively protect your valuable prep columns from the damaging effects of mobile phase and sample chemical contaminants and particulates, without altering your chromatographic results.
- Extends preparative column lifetime by as much as 5 times
- Protects column from samples that precipitate out of solution
- Protects column from contaminants
- Stable and leak free up to 60 mL/min within specified pressure ratings
Lower Cost Per Injection
Forced Degradation Study
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Columns:
Luna® 10 µm C18(2) Axia Packed
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Dimension:
50 x 21.2 mm
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Mobile Phase:
A: 0.1 % TFA in Water
B: 0.1 % TFA in Water / Acetonitrile (25:75)
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Injection Volume:
420 µL
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Gradient:
Linear 93:7 (A/B) to 100 % B over 5 minutes
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Flow Rate:
60 mL/min
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Temperature:
Ambient
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Detection:
UV @ 270 nm
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Sample:
1. Nadolol
2. Metoprolol
3. Propranolol
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