Strata SE (Synthetic Extraction) SLE Products

Strata SE SLE is an advanced sample preparation solution designed for low-level extractions, delivering high recoveries and clean extracts from biological samples. It has demonstrated batch-to-batch consistency and is QC-tested by LC-MS/MS to ensure minimal background interference and reliable performance.

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SP
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3051
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Overview

Designed for low level extractions. Interference free.

Strata SE SLE produces high-quality, clean extracts providing superior results to laboratories seeking more sustainable solutions to respond to health concerns from the use of halogenated solvents. Recoveries and %CV of 11 steroids extracted from Strata SE, and Competitor SLE at LOD eluted with Ethyl Acetate.

A Simple 3-Step Method

Strata SE SLE delivers clean extracts and high recoveries.

Step 1: Load

Step 2: Wait

Step 3: Elute

LOD Comparison of 11 steroids: Strata SE SLE vs. Competitor SLE

Peak No.
Analyte
Retention Time (RT)
LOD
Units
Ionization
1
Aldosterone
1.8
10
pg/mL
Negative
2
18-OH-Corticosterone
2
150
pg/mL
Positive
3
21-Deoxycortisol
3.1
40
pg/mL
Positive
4
11-Deoxycortisol
3.4
20
pg/mL
Positive
5
Androstenedione
3.8
10
pg/mL
Positive
6
Estrone
3.9
20
pg/mL
Negative
7
11-Deoxycorticosterone
4
50
pg/mL
Positive
8
Estradiol
4.1
40
pg/mL
Negative
9
Estradiol
4.1
40
pg/mL
Negative
10
17-OH-Progesterone
4.3
150
pg/mL
Positive
11
Progesterone
5
150
pg/mL
Positive

Recovery and %CV of 11 Steroids at LOD Eluted with Ethyl Acetate

Analyte
Strata SE SLE - % Recovery
% CV
Competitor SLE - % Recovery

% CV
18-OH-Corticosterone
98

7.9

61

54
21-Deoxycortisol
99
2.9
61
3.9
11-Deoxycortisol
73
8.5
68
6.5
Androstenedione
113
8.8
58
6
11-Deoxycorticosterone
117
15
64
5.5
Testosterone
118
5.2
63
8.9
17-OH-Progesterone
109
2.3
73

12.4
Progesterone
83
12
49

5.7
Aldosterone
103
11
74
25
Estrone
107
6.9
82
8.5
Estradiol
113
12.8

91
10.9

Consistent Performance Batch-to-Batch Analyte % Recovery at LOD

Product consistency batch-to- batch delivers robust and reproducible results for high sensitivity analytical methods.