Ion-exchange (IEX) chromatography involves interactions between a charged stationary phase and the oppositely charged mobile analytes. In cation-exchange chromatography positively charged molecules are attracted to a negatively charged stationary phase. Likewise, in anion-exchange chromatography negatively charged molecules are attracted to a positively charged stationary phase.
Ion-exchange (IEX) chromatography is useful for a wide variety of compounds, such as acidic (anionic) and basic (cationic) small molecules up to peptides and proteins.
Brand | Description: |
---|---|
Luna SCX | Strong selectivity for positively charged compounds |
bioZen WCX | Efficient weak cation exchange phase that allows you to separate proteins (especially monoclonal antibodies) from acidic/basic variants |
PhenoSphere SAX | Fully porous 80A strong anion-exchanger |