Biozen dSEC-2
Hydrophilic Diol-Bonded SEC Chemistry for Protein and Biotherapeutic Characterization
As part of the Biozen™ dSEC family, Biozen dSEC-2 columns combine controlled pore silica particles with a proprietary hydrophilic diol-bonded surface chemistry designed to minimize secondary interactions and enable reliable size-based separations of proteins and biomolecules.
- Optimized Pore Structure for Protein Separations
- Exceptional Stability and Column Lifetime
- Reproducible SEC Performance Batch After Batch
Hydrophilic Diol-Bonded SEC Chemistry for Protein and Biotherapeutic Characterization
As part of the Biozen™ dSEC family, Biozen dSEC-2 columns combine controlled pore silica particles with a proprietary hydrophilic diol-bonded surface chemistry designed to minimize secondary interactions and enable reliable size-based separations of proteins and biomolecules.
- Optimized Pore Structure for Protein Separations
- Exceptional Stability and Column Lifetime
- Reproducible SEC Performance Batch After Batch
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Overview
Biozen SEC Proprietary Silica Particle Technology
The Biozen dSEC columns are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with protein samples.
Biozen SEC Hydrophilic Surface Chemistry Improves Aggregate Analysis
Improved Column Lifetime and Performance Stability
Phenomenex’s optimized SEC column loading technology has significantly improved the overall packing density and silica distribution of the columns leading to improved chromatographic lifetime and stability.
Unchanged Performance After 300 Injections
Unchanged Performance After 100 Hours of Extreme Running Conditions
New Standard for Platform SEC Methods
Whether IgG2 or IgG4 isotypes, bispecifics, or Fc-Fusions, dSEC-2 provides excellent separation and sample recovery for many different classes of antibodies and related recombinant proteins.
Conditions for both separations:
Sample:
As noted