Kinetex Phenyl-Hexyl Core-Shell Column

DNA, RNA, miRNA, siRNA, phosphorothioates, LNA, single stranded, duplexed, and encapsulated oligonucleotides. As long as there is a phosphodiester or phosphorothioate backbone the extraction protocol should provide excellent clean-up and recovery

Due to the polar nature of phenyl phases they can be used under 100% aqueous mobile phases without the user being concerned about phase collapse.

Kinetex phenylhexyl is best suited to the separation of aromatic compounds which are relatively hydrophobic. It can also be used as an alternate selectivity to a C8 or C18, retaining compounds to a similar extend compared to a C8, but with the additional pi-pi interations allowing for aromatic positional isomers to be separated. Kinetex biphenyl is more applicable to polar aromatic compounds, and will also offer a good degree of shape selectivity. Kinetex F5 is the most polar phenyl phase, due to it's highly polar nature and the interactions it can undergo with analytes it is the best option for analyzing highly polar analytes, and those compounds which differ in terms of pi electron structure.