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Product Information
Phase Detail
Strata-X-CW SPE Products
Strata-X-CW solid phase extraction (SPE) sorbent is a polymeric strong cation exchange sorbent that can be used to cleanup weak bases

Strata-X-CW SPE Products

Weak Cation Mixed-Mode Solid Phase Extraction (SPE)

A weak cation-exchange functionalized polymeric sorbent that allows for complete retention of basic compounds with a pKa greater than 8, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.

Recommended Use
Extraction of basic compounds, particularly strong bases

Long Column Lifetimes and Excellent Performance

Weak Cation-Exchange

π-π Bonding

Hydrophobic Interaction

Available Formats

Strata 96 Well Plate
96-Well Plates
Microelution 96-Well Plates
1, 3, and 6 mL Tubes
Giga™ Tubes (12-150 mL Tubes)
On-line Cartridges

Starting Method

For Bases with pKa > 8

1 mL Methanol
1 mL Water, pH 6-7
Diluted Sample, pH 6-7
Wash 1:
1 mL Water, pH 6-7
Wash 2:
1 mL Methanol (collect this fraction to analyze Neutrals/Acids)
Elute Any Bases:
2x 500 µL 5 % Formic Acid in Methanol
Elute Weak Bases:
2x 500 µL 5 % NH4OH in Methanol

Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.