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Product Information
Phase Detail
Strata-XL-C SPE Products
Strata-X-L-C solid phase extraction (SPE) sorbent is a polymeric large particle strong cation exchange (SCX) phase SPE sorbent for viscous samples

Strata-XL-C SPE Products

Large Particle Strong Cation Mixed-Mode Solid Phase Extraction (SPE)

A strong cation-exchange functionalized polymeric sorbent that allows for complete retention of basic compounds with a pKa less than 10.5, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.  The large particle format is ideal for processing large volumes or viscous samples.

Recommended Use
Extraction of weakly basic compounds, present in large volume or viscous samples

3 Mechanism of Retention

Strong Cation-Exchange

π-π Bonding

Hydrophobic Interaction

Available Formats

Strata 96 Well Plate
96-Well Plates
1, 3, and 6mL Tubes
Giga Tubes (12-150mL Tubes)

Starting Method

For Bases with pKa ≤ 10.5

1 mL Methanol
1 mL Acidified Water
Diluted Acidified Sample
Wash 1:
1 mL 0.1 N HCI in Water (collect this fraction to analyze Polar Neutrals)
Wash 2:
1 mL 0.1 N HCI in Methanol (collect this fraction to analyze Neutrals/Acids)
Elute Any Acids:
2x 500 µL 5 % NH4OH in Methanol

Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.