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Albuterol & Ambroxol in Oral Solution
The active ingredients albuterol and ambroxol are relatively polar drug substances that present a reversed phase retention challenge. To promote increased retention and selectivity, several methods have outlined the use of ion-pairing agents in the mobile phase. In this application, we investigated a reversed phase method that instead leveraged the increased polar retention and selectivity of the Kinetex Polar C18.

Albuterol & Ambroxol in Oral Solution

The active ingredients albuterol and ambroxol are relatively polar drug substances that present a reversed phase retention challenge. To promote increased retention and selectivity, several methods have outlined the use of ion-pairing agents in the mobile phase. In this application, we investigated a reversed phase method that instead leveraged the increased polar retention and selectivity of the Kinetex Polar C18.
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Document Type:
Technical Notes
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Separation Modes:
Reversed Phase

Albuterol & Ambroxol in Oral Solution

The active ingredients albuterol and ambroxol are relatively polar drug substances that present a reversed phase retention challenge. To promote increased retention and selectivity, several methods have outlined the use of ion-pairing agents in the mobile phase. In this application, we investigated a reversed phase method that instead leveraged the increased polar retention and selectivity of the Kinetex Polar C18.

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