- Generic SPE Method by Retention Mechanism
- How is normal phase SPE different from reversed phase SPE? How do I decide which one to use?
- How much sample can I load onto my SPE device? Is it linked to the concentration of my analyte of interest?
- VIDEO Are you using the right SPE wash step?
- What is the Matrix Effect?
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SPE Knowledge Center
What is Sample Preparation Extraction?
Sample preparation, often referred to as sample prep, is a crucial step in analytical workflows that allows scientists to obtain precise and dependable results. It involves a series of techniques aimed at extracting, purifying, and concentrating target analytes from complex matrices. Whether you are analyzing environmental, food and beverage, or pharmaceutical samples, proper sample preparation is key to ensuring the efficiency and accuracy of your analysis.
Technical Tips
Fundamental
Application
- Considerations when working with solid samples and SPE
- Sample Pre-treatment Procedures for Bioanalytical Samples
- Peptide Mapping Sample Prep - Good Practices for Tryptic Digests
- Sample prep for N-linked Glycans - The use of a sample prep plate for cleaning up N-linked glycans cleaved from glycoproteins
- Sample Preparation for Oligonucleotides
- All My Analytes are Neutrals, but Contaminants are Acids or Amines. What is the Best Way to Concentrate and Clean Up my Analytes of Interest?
Troubleshooting
- Over-Drying of Silica-Based SPE Cartridges Can Lead to Poor Sample Recovery
- Troubleshooting SPE
- I am getting low recovery in my SPE method, how do I fix the problem?
- VIDEO My recovery is lower than expected after my SPE method. Why and how can I fix it?
- Why are my recoveries greater than 100%?
- VIDEO My Sample Won’t Flow Through My SPE Cartridge, Why Is This Happening?
- SPE Troubleshooting - Extra Peak
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.