Phenomenex Introduces Clarity OTX Pro, A Next-Gen Solid Phase Extraction (SPE) Sample Preparation Kit for Oligonucleotide Bioanalysis

Standardization with Minimal Method Optimization for Oligos and Oligo-Conjugates

September 30, 2025

TORRANCE, CA - Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, proudly announces the launch of Clarity OTX Pro, a next generation SPE product. As oligonucleotide biotherapeutics become more prominent, bioanalytical scientists are facing challenges in optimizing extraction procedures for LC-MS/MS analysis due to resource inefficiencies. The Clarity OTX Pro extraction kit is designed to deliver cleaner extracts and higher oligonucleotide recoveries from complex biological matrices.

”With our original method, we see poor peak shape and lose resolution,” says Ian Dawson, Principle Method Development Scientist at Agilex Bio. “Using your Clarity OTX Pro extraction kit chromatography is excellent, with consistent extraction performance and ~90% recovery with no method optimization.”

This extraction kit addresses challenges such as day-to-day variability, lengthy optimization time, and compromised data quality in bioanalysis via LC-MS/MS analysis. Thus, enabling confidence when making critical drug efficacy decisions.

This latest innovation from Phenomenex Inc., is part of our commitment to being a leader in chromatography solutions, empowering researchers and scientists with tools tailored to advance the frontiers of biotherapeutics. For more information about this product, please get in touch with our technical experts.

About Phenomenex
Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in academic, pharmaceutical, biotech, environmental, clinical research, government, and industrial laboratories. From drug discovery and pharmaceutical development to food safety and environmental analysis, Phenomenex chromatography solutions accelerate science and help researchers improve human health and well-being. Phenomenex is an operating company within Danaher Corporation’s Life Sciences platform.

For more information, please visit www.phenomenex.com and follow the company's blog

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Contact Information: Jannette Avila, Senior Manager, Brand and Public Relations jannettea@phenomenex.com | M: +1 (310) 212-0555