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Clarity SPE
Product Information
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Explore ClaritySPE™ oligonucleotide purification products by Phenomenex for efficient extraction and reliable, reproducible results in your analyses. Read more.
The Clarity BioSolutions sample preparation portfolio is composed of unique solid phase extraction chemistries packed in 96-well plate and cartridge formats designed to efficiently and effectively purify oligonucleotides.
- Works for desalting and clean up of biological samples
- Specially formulated buffer solutions available for optimal performance
- Quick protocols for rapid LC-MS/MS results
- No liquid-liquid extractions (LLE)
Oligonucleotide Purification Products
Clarity OTX™ SPE
Prior to LC-MS analysis, therapeutic oligonucleotides must be isolated from interferences such as salts, sugars, large proteins, and genomic DNA. Using a mixed-mode solid phase extraction (SPE) sorbent in conjunction with carefully formulated buffers, Clarity OTX consistently delivers high recoveries.
Material Characteristics
| Clarity Products | Particle Support | Bonded Phase | Particle Shape/Size (μm) | Pore Size(Å) | Surface Area (m2/g) |
|---|---|---|---|---|---|
Polymer (surface modified PSDVB) |
Mixed-mode anion exchanger |
33 |
85 |
800 |
|
Polymer (PSDVB) |
Hydrophilic polymer coating |
35 |
500 |
300 |
|
Silica |
C18 |
55 |
140 |
300 |
Clarity OTX and Clarity QSP are patented by Phenomenex. U.S. Patent No. 7,119,145
Clarity BioSolutions Product Selection
Purification
Characterization / Analysis
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.