Product Information
Phase Detail
Kinetex Core-Shell C18 HPLC Column
C18 HPLC Column - Kinetex core-shell C18 columns offer increased efficiencies over traditionally porous C18 LC columns on HPLC/UHPLC systems
Kinetex Core-Shell C18 HPLC Column
Kinetex Core-Shell C18 HPLC Column
The Go-To Core-Shell Selectivity for Hydrophobic Compounds!
The well-rounded, all-purpose core-shell Kinetex C18 HPLC column produces increased efficiencies over traditional, fully porous columns. Yielding remarkable chromatographic resolution, higher peak capacities, and greater sensitivity, so labs can get the most out of every HPLC or UHPLC analysis.
- Compatible with all Analytical HPLC/UHPLC Systems*
- Four fully scalable particle sizes available
- Excellent Reproducibility and Batch-to-Batch Confidence
- USP: L1
*Kinetex C18 analytical columns are compatible with all LC system with standard LC column end-fittings threaded in 10-32. Please contact us for any questions and information about fitting compatibility and any other column internal diameters.
Carbon Load 12 (effective), null %, 12 (effective) % |
Surface Area (m²/g) 200 |
Particle Size 1.3, 1.7, 2.6, 5 |
Recommended Use All-purpose hydrophobic retention and methylene selectivity |
Balances Retention and Performance
Balanced C18 phase that provides the highest degree of hydrophobic selectivity relative to the other Kinetex phases.
Upgrade from Traditional Fully Porous to Kinetex Core-Shell
Instantly get more out of your analytical method and upgrade to the Kinetex C18. Take advantage of the fully scalable available particle sizes of Kinetex C18 to bring improved performance to any LC system!
1.7 µm Fully Porous vs. 1.7 µm Core-Shell
Conditions for both columns:
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Columns:
Kinetex 1.7 µm C18
Traditional 1.7 µm C18 |
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Dimension:
50 x 2.1 mm
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Mobile Phase:
Acetonitrile / Water (50:50)
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Flow Rate:
0.6 mL/min
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Temperature:
25 °C
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Detection:
UV @ 254 nm
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Instrument:
*Waters® ACQUITY® UPLC®
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Sample:
1. Acetophenone
2. Benzene 3. Toluene 4. Naphthalene |
Fully Porous vs. Core-Shell
◊ Signal-to-noise ratio of peak 2; ∆ Based on average peak widths; *Waters, ACQUITY, and UPLC are registered trademarks of Waters Corporation. Phenomenex is not affiliated with Waters Corporation. Comparative separations may not be representative of all applications. Conditions same for both columns except where noted.
Conditions for both columns:
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Columns:
Kinetex 2.6 µm C18 100 Å
Traditional 5 µm ODS-3 100 Å |
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Dimension:
Kinetex: 150 x 4.6 mm
Traditional: 250 x 4.6 mm |
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Mobile Phase:
A: 0.1 % Phosphoric acid in Water
B: 0.1 % Phosphoric acid in Acetonitrile |
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Gradient:
5 % to 95 % B in 9 min (150 x 4.6 mm)
5 % to 95 % B in 15 min (250 x 4.6 mm) |
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Flow Rate:
1.8 mL/min
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Temperature:
50 °C
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Detection:
UV @ 215 nm (22 °C)
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Sample:
1. Procainamide
2. Acetaminophen 3. Folic acid 4. Sulfathiazole 5. Acebutolol 6. Dextromethorphan 7. Diphenhydramine 8. Propafenone 9. Amitriptyline 10. Fluoxetine 11. Naproxen 12. Diflunisal 13. Indomethacin |
Performance with Kinetex C18 on HPLC and UHPLC Systems
Quickly improve the productivity and performance of your existing methods and utilize the core shell advantage to deliver performance you need at backpressures the system can handle.
Fully Porous vs. Core-Shell
*Agilent 1100 was optimized with the Core-Shell Performance Enhancement Kit AQ0-8892. Agilent and ZORBAX are registered trademarks of Agilent Technologies, Inc. Phenomenex is not affiliated with Agilent Technologies. Comparative separations may not be representative of all applications.
Columns:
Kinetex 2.6 µm C18 (Agilent 1100*)
Kinetex 2.6 µm C18 (Agilent 1290) ZORBAX 1.8 µm SB-C18 (Agilent 1290) |
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Dimension:
100 x 4.6 mm
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Mobile Phase:
A: Water with 0.1% TFA B: Acetonitrile with 0.1% TFA |
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Gradient:
Time (min)
0
20 | % B
10 70 |
Flow Rate:
1.2 mL/min |
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Temperature:
Ambient |
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Detection:
UV @ 210 nm |
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Sample:
Mupirocin degradants |
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