Sample Prep|Brands|Novum Supported Liquid Extraction (SLE) Plates
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Novum Supported Liquid Extraction

Simplify Your Liquid-Liquid Extractions with Faster, Easier, and More Reliable SLE

Novum Supported Liquid Extraction (SLE) (patent pending) products are a  faster, easier, and more reliable way to perform liquid-liquid extractions. In 3 easy steps and less than 15 minutes, you can remove unwanted interferences such as salts, proteins, phospholipids and more from a variety of samples without performing extensive method development.

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Overview

Supported Liquid Extraction Made Simple

Novum SLE will instantly increase your throughput by eliminating time consuming steps and reducing the risk of analyte loss. If further time savings are necessary, Novum SLE can be easily automated for rapid, hands free sample cleanup.

Slow and Laborious

Fast and Easy

Traditional Liquid-Liquid Extraction1

Estimated Time per Sample = 25 minutes

Novum Supported Liquid Extraction (SLE)

Estimated Time per Sample = < 15 minutes

1. Dilute sample 1:1 with buffer or water and add extraction solvent
1. Dilute sample 1:1 with buffer or water and load onto Novum SLE sorbent using 2–15 seconds of vacuum
2.Mix for 10 minute
2.Wait 5 minutes
3.Centrifuge for 10 minutes
3. Apply elution solvent and allow to elute via gravity. Complete elution with 10 seconds of vacuum.
4.Pour off or freeze supernatant
  • Rapid, automatable method for high-throughput cleanup
  • Stop worrying about analyte loss due to emulsions

1. Russell Grant, Matthew Crawford, Brian Rappold, and Stacy Dee.  Errors in Bioanalysis Due to Phospholipids – Definitive Measurement, Mechanism, and Management.  ASMS 2011.

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