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Product Information
Novum Simplified Liquid Extraction
Novum supported liquid extraction (SLE) products offer streamlined sample preparation over liquid liquid extraction.
SPE Background

Novum Simplified Liquid Extraction

Simplify Your Liquid-Liquid Extractions with Faster, Easier, and More Reliable SLE

Novum Simplified Liquid Extraction (SLE) (patent pending) products are a  faster, easier, and more reliable way to perform liquid-liquid extractions.  In 3 easy steps and less than 15 minutes, you can remove unwanted interferences such as salts, proteins, phospholipids and more from a variety of samples without performing extensive method development.

New Novum PRO SLE to get down to low (LLOD) extraction levels from plasma

Novum SLE Products
Novum Simplified Liquid Liquid Extraction Plates

A Simplified Liquid Extraction

Novum SLE will instantly increase your throughput by eliminating time consuming steps and reducing the risk of analyte loss. If further time savings are necessary, Novum SLE can be easily automated for rapid, hands free sample cleanup.

Slow and Laborious

Liquid-Liquid Extraction1

Estimated Time per Sample = 25 minutes


Dilute sample 1:1 with buffer or water and add extraction solvent


Mix for 10 minutes


Centrifuge for 10 minutes


Pour off or freeze supernatant

Fast and Easy

Novum Simplified
Liquid Extraction (SLE)

Estimated Time per Sample = < 15 minutes


Dilute sample 1:1 with buffer or water and load onto Novum SLE sorbent using 2–15 seconds of vacuum


Wait 5 minutes


Apply elution solvent and allow to
elute via gravity. Complete elution
with 10 seconds of vacuum.

  • Rapid, automatable method for high-throughput cleanup
  • Stop worrying about analyte loss due to emulsions

1. Russell Grant, Matthew Crawford, Brian Rappold, and Stacy Dee.  Errors in Bioanalysis Due to Phospholipids – Definitive Measurement, Mechanism, and Management.  ASMS 2011.