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Kinetex Core-Shell Technology Columns

Product Information
Brand
The Core-Shell Advantage
Kinetex HPLC Column - Unlock unparalleled efficiency in HPLC with Kinetex Core-Shell Columns by Phenomenex. Optimize performance and reduce costs effortlessly.

The Core-Shell Advantage

Kinetex Core-Shell Technology delivers dramatic improvements in efficiency over conventional fully porous media, which can be leveraged to increase resolution, greatly improve productivity, reduce solvent consumption, and decrease costs. Whether you are running HPLC or UHPLC methods, the Kinetex core-shell family can deliver shockingly improved performance over the current column you are using. Phenomenex designs, manufactures, and sells its very own silica and organo-silica core-shell particles. The combination of a consistent, solid, high-density core along with proprietary column packing technologies in the Kinetex HPLC column ensures optimum bed structure and high column performance.

  • Performance gains on ANY LC system
  • System-to-system and lab-to-lab method portability
  • Improve the productivity of older, established methods 


Kinetex Core-Shell Technology
Kinetex Core-Shell Technology Columns

Kinetex Core-Shell Performance on Any LC System

The 5 versatile particle sizes allow you to select the best fit for your instrument .
Kinetex 1.3µm
UHPLC
Kinetex 1.7µm
UHPLC
Kinetex 2.6µm
UHPLC/HPLC
Kinetex 3.5µm
HPLC
Kinetex 5µm
HPLC/PREP

Particle Chemistry

Using sol-gel processing techniques that incorporate nano-structuring technology, a durable, homogeneous porous shell is grown on a solid silica core to create a Kinetex Core-Shell particle. This particle morphology results in less band broadening for all four sources of UHPLC band broadening compared to fully porous particles and thus delivers extremely high efficiencies.

  • Optimized for Ultra-High Performance
  • Superior Core-Shell Quality
  • Core-Shell Scalability and Portability

 

Kinetex Polar C18

Kinetex Polar C18

Minimized Band Broadening

Fully Porous

Fully Porous

Increased Band Broadening


Expand Your Core-Shell Selectivity Toolbox

Choose from 11 high-performing stationary phases available.

Kinetex Phases
Shipping Solvent
Particle
Sizes
(µm)
Pore
Size
(Å)
Surface
Area
(m2/g)
Carbon
Load
(%)
pH Stability
Reversed
Phase
Normal
Phase
HILIC
100%
Aqueous
Stable
Acetonitrile / Water (50:50)
2.6
100
200
9
1.5-8.5*


Acetonitrile / Water (50:50)
2.6
100
200
9
1.5-8.5*


Acetonitrile / Water (50:50)
1.3, 1.7, 2.6, 5
100
200
12
1.5-8.5*



Acetonitrile / Water (45:55)
1.7, 2.6, 5
100
200
11
1-12


Acetonitrile / Water (50:50)
1.7, 2.6, 3.5, 5
100
200
10
1.5-8.5*



Acetonitrile / Water (45:55)
1.7, 2.6, 5
100
200
8
1.5-8.5*



Acetonitrile/Water w/
0.1 % Formic Acid (50:50)
1.7, 2.6, 5
100
200
11
1.5-8.5*


Acetonitrile / Water (45:55)
1.7, 2.6, 5
100
200
11
1.5-8.5*



Acetonitrile / Water (40:60)
1.7, 2.6, 5
100
200
9
1.5-8.5*

 
Acetonitrile /
100 mM Ammonium Formate (93:7)
1.7, 2.6, 5
100
200
0
2.0-7.5

 

Acetonitrile / Water (65:35)
3.5
12
1.5-8.5*





† Shipping conditions may vary slightly in terms of organic to aqueous ratio, depending on column dimensions. * pH stability under gradient conditions. pH stability is 1.5-10 under isocratic conditions.

Core-shell vs Fully Porous

High Efficiency‚ High Density Particle

Achieve Sub-2 μm Performance within HPLC Backpressure Limitations

Conditions for both columns:

Columns:
Kinetex 2.6 µm C18
Traditional 1.7 µm C18
Dimension:
50 x 2.1 mm
Mobile Phase:
Acetonitrile / Water (50:50)
Flow Rate:
0.6 mL/min
Temperature:
25 °C
Detection:
UV @ 254 nm
Instrument:
Waters® ACQUITY® UPLC®
Sample:
0.5 µL test mixture
1. Acetophenone
2. Benzene
3. Toluene
4. Naphthalene

Superior Core-Shell Quality

Uniform Particle Size Distribution

To ensure reproducible, robust, and reliable results, Kinetex core shell HPLC columns are manufactured with high-quality standards. Every step in the manufacturing process of Kinetex core shell columns is tightly controlled for

 

  • Particle size distribution
  • Surface and bonding homogeneity
  • Selectivity quality control testing
  • Inertness of the base silica
  • Packing quality and consistency

 

Batch-to-Batch Reproducibility Overlay

Comparative separations may not be representative of all applications.

Columns:
Kinetex 2.6 µm C18
Dimension:
50 x 4.6 mm
Part No.:
00B-4462-E0
Mobile Phase:
Water / Acetonitrile (65:35)
Flow Rate:
1.0 mL/min
Temperature:
25 °C
Detection:
UV @ 254 nm
Sample:
1. Uracil
2. Hydrocortisone
3. Cortisone
4. Cortisone acetate
5. 17-Hydroxyprogesterone