Sample Preparation Techniques
There are many types of sample preparation techniques offered from Phenomenex, each suited for specific types of analyses and sample matrices based on the needs for the final sample. These methods are essential in preparing samples for further analysis by LC or GC. Selection of the proper sample preparation technique depends on factors such as the type of the sample, the analytes of interest, sensitivity requirements, time available and ensuring that the sample is in the optimal state for accurate and precise analysis.
Solid Phase Extraction (SPE)
A multi-step separation process used in analytical labs to isolate and concentrate target compounds from complex mixtures, removing interferences and matrix components for analysis.
Supported Liquid Extraction
A faster, easier, and more reliable liquid-liquid extraction method that removes proteins, salts, and phospholipids with less solvent and time.
Filtration
A mechanical process that separates solids from fluids using a medium that lets only the fluid pass through.
Protein Precipitation
Protein-rich samples like blood, plasma, or serum may require protein aggregation to enable their removal
Phospholipid Removal
In biological sample analysis, phospholipid removal eliminates compounds that cause ion suppression and matrix effects in MS.
Immunocapture
Paramagnetic beads used to capture streptavidin or other target analytes using a magnetic force to separate and perform a clean-up of biologics for peptide mapping or peptide quantitation.
QuEChERS
A simplified method for analyzing multi-residue pesticides in food and environmental samples. The name combines 'Quick, Easy, Cheap, Effective, Rugged, and Safe.
Beta Glucuronidase Removal
A rapid B-Glucuronidase clean-up method for hydrolyzed urine, enabling drug testing in under a minute—ideal for clinical research labs.